DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and OVCH1

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	263	Identity:	85/263 - (32%)
Similarity:	130/263 - (49%)	Gaps:	46/263 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RW-EQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVR 85
            :| .:||.|||.......||||.|::.||:.|||:|.:...|:||||| ...:.|.|   .:.:.
Human   604 QWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHC-VQLKNNPL---SWTII 664

  Fly    86 AGS---ALTDSNGTLVDVAALIIHEEY---AFDLNINDIAIVRLSTPLEFTSKVQPI--PLAKTN 142
            ||.   .|.:|...:.....:|:||::   ::|   :|||:::||:|||:.|.|:|:  |.:...
Human   665 AGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYD---SDIALIQLSSPLEYNSVVRPVCLPHSAEP 726

  Fly   143 PYPRSIALVSGWG-VSYILNDSTNLYPTHLQGLALHIKSIFSCRL---------FDPSLLCAG-- 195
            .:...|..|:||| :|     :.....:.||.:.:|:.....|..         ....::|||
Human   727 LFSSEICAVTGWGSIS-----ADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFA 786

  Fly   196 -TYGRTACHGDSGGPLVVNKQ-----LVGVVSWGRKGCV---SSAFFVSVPYFREWI---LNAIA 248
             :..:..|.||||||||...:     |.|:|||| .|||   ....|..|..|.:||   :|..|
Human   787 ASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWG-AGCVQPWKPGVFARVMIFLDWIQSKINGPA 850

  Fly   249 SIQ 251
            |:|
Human   851 SLQ 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	78/245 (32%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	77/244 (32%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	79/247 (32%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910