DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	241	Identity:	82/241 - (34%)
Similarity:	120/241 - (49%)	Gaps:	37/241 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGSAL 90
            ||..|:|......|||.|||..|.|:||.|:.....:||:||||.:.:..:|    :.|..|..|
Mouse   185 RIADGKPADKASWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPKL----WTVSFGRTL 245

  Fly    91 TDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPI--PLAKTNPYPRSIALVSG 153
            : |..|...|.::|:||.||...:.:|||:|:||:|:.|:..:..:  |.|.....|:|...|:|
Mouse   246 S-SPLTTRKVESIIVHENYASHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKVFVTG 309

  Fly   154 WGVSYILNDSTNLYPTHLQGLALHIKSIFSCR-------LFDPSLLCAG--TYGRTACHGDSGGP 209
            ||..    .:...:|..||.:.:.|.|...|.       .....::|||  |....||.||||||
Mouse   310 WGAL----KANGPFPNSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGP 370

  Fly   210 LVV----NK-QLVGVVSWG-------RKGCVSSAFFVSVPYFREWI 243
            ||:    || .|:|:||||       :.|     .:..|.::|:||
Mouse   371 LVISDNRNKWYLLGIVSWGIDCGKENKPG-----IYTRVTHYRDWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	80/239 (33%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	79/238 (33%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	80/239 (33%)
		Tryp_SPc	186..414	CDD:238113	81/240 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910