DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and HABP2

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	284	Identity:	70/284 - (24%)
Similarity:	110/284 - (38%)	Gaps:	73/284 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FLSAGQ---VNRWEQRIIGGEPIGIEQVPWQVSLQYF--------GDHVCGGSIYSENIIVTAAH 67
            |.|.|:   ..|..:||.||......:.|||.|||..        ..|.|||::.....::||||
Human   298 FDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAH 362

  Fly    68 CF-------------FDEEGNRLDDQGYQVRAGSALTDSNGTLVDVAALIIHEEYAFDLNINDIA 119
            |.             .|.:.....:|.::              |:......|.....::..||||
Human   363 CTDIKTRHLKVVLGDQDLKKEEFHEQSFR--------------VEKIFKYSHYNERDEIPHNDIA 413

  Fly   120 IVRLSTPLEFTSKVQPIP--LAKTNPYPRSIAL------------VSGWGVSYILNDSTNLYPTH 170
            ::          |::|:.  .|..:.|.:::.|            :|||||:.....|..|....
Human   414 LL----------KLKPVDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAK 468

  Fly   171 LQGLA---LHIKSIFSCRLFDPSLLCAGTY---GRTACHGDSGGPLVVNKQ----LVGVVSWGRK 225
            ::.:|   .:.:.::. .:.|.|::|||..   |:..|.|||||||...|.    :.|:||||.:
Human   469 VKLIANTLCNSRQLYD-HMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLE 532

  Fly   226 GCVSSAFFVSVPYFREWILNAIAS 249
            .......:..|..|..||...|.|
Human   533 CGKRPGVYTQVTKFLNWIKATIKS 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	62/261 (24%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	61/260 (23%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	63/263 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910