DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Tmprss5

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_695223.2	Gene:	Tmprss5 / 266681	RGDID:	628625	Length:	445	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	87/248 - (35%)
Similarity:	124/248 - (50%)	Gaps:	38/248 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAG--- 87
            ||:||:.:...:.|||.|:.....|.||.|:.:...:||||||.:....:||  ..::|.||
  Rat   207 RIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMYSFRLSRL--SSWRVHAGLVS 269

  Fly    88 -SALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPIPL-AKTNPYPR-SIA 149
             ||:....||:|:  .:|.|..|:...:..|:|:::|.||:.|:..|..:.| ||...:|: |..
  Rat   270 HSAVRQHQGTMVE--KIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQHFPQGSQC 332

  Fly   150 LVSGWGVSYILNDSTNLYPTH----LQGLALHIKSIFSCR---LFDPSL----LCAGTY-GRT-A 201
            .|||||       .|:...||    ||...:.:.|...|.   ::..:|    ||||.. ||. |
  Rat   333 WVSGWG-------HTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLDGRADA 390

  Fly   202 CHGDSGGPLVVNK----QLVGVVSWGRKGCVS---SAFFVSVPYFREWILNAI 247
            |.||||||||...    .||||||||| ||..   ...:..|..|.:||.:.:
  Rat   391 CQGDSGGPLVCPSGDTWHLVGVVSWGR-GCAEPNRPGVYAKVAEFLDWIHDTV 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	85/242 (35%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	84/241 (35%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:406055
Tmprss5	NP_695223.2	Tryp_SPc	208..441	CDD:238113	86/244 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910