DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	246	Identity:	82/246 - (33%)
Similarity:	110/246 - (44%)	Gaps:	43/246 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGS 88
            |:|||||........|||||||....|.|||::.|...::||||||     ....:..|......
Mouse   183 EERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCF-----KSYPNPQYWTATFG 242

  Fly    89 ALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPI--PLAKTNPYPRSIALV 151
            ..|.|....|.|.|::.|:.|:.....||||:|:|...:.|:..:..:  |.|..|..|.|:|.|
Mouse   243 VSTMSPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAYV 307

  Fly   152 SGWG-VSYILNDSTNL--------------YPTHLQGLALHIKSIFSCRLFDPSLLCAGTYGRT- 200
            :||| ::|..|..|||              .|....|..|            |.:||||.....
Mouse   308 TGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVL------------PGMLCAGMRSGAV 360

  Fly   201 -ACHGDSGGPLVVNKQ-----LVGVVSWGRKGCVSS--AFFVSVPYFREWI 243
             ||.||||||||....     :||:||||.:..:.:  ..:..|..:|.||
Mouse   361 DACQGDSGGPLVQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	79/242 (33%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	78/241 (32%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	79/242 (33%)
		Tryp_SPc	186..414	CDD:238113	80/243 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910