DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Prss40

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_033382.2	Gene:	Prss40 / 21756	MGIID:	1270857	Length:	365	Species:	Mus musculus

Alignment Length:	263	Identity:	81/263 - (30%)
Similarity:	127/263 - (48%)	Gaps:	42/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LSAGQV---NRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNR 76
            ||..:|   .:::.:|.||:..|.|:.|||.||:.:|.|:||..:..:|.:::|||||...:
Mouse    54 LSLSEVCGKTKFQGKIYGGQIAGAERWPWQASLRLYGRHICGAVLIDKNWVLSAAHCFQRSQ--- 115

  Fly    77 LDDQGYQVRAGSALTDSN-----GTLVDVAALIIHEEY-AFDLNINDIAIVRLSTPLEFTSKVQP 135
             :...|.|..|  .||.|     ...:.|..:|:|::| .|....:||.:::|.:.:|::|.:.|
Mouse   116 -EPSDYHVMLG--YTDLNSPTRYSRTMSVQKVIVHKDYNRFHTQGSDIVLLQLRSSVEYSSHILP 177

  Fly   136 IPLAKTN-PYPRSIAL-VSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRLFDP--------- 189
            ..:.:.| ..|:..|. .||||  |:..|.....|..|....|.|.|...|:.|.|
Mouse   178 ACVPEENIKIPKEKACWASGWG--YLREDVRIPLPNELYEAELIIMSNDQCKGFFPPPVPGSGRS 240

  Fly   190 -----SLLCAGTY--GRTACHGDSGGPLVV----NKQLVGVVSWG---RKGCVSSAFFVSVPYFR 240
                 .::||..|  .::.|.||||||||.    :..:||:.||.   .:..||.:.|..|.||.
Mouse   241 YYIYDDMVCAADYDMSKSICAGDSGGPLVCLLEGSWYVVGLTSWSSTCEEPIVSPSVFARVSYFD 305

  Fly   241 EWI 243
            :||
Mouse   306 KWI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	76/247 (31%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	76/246 (31%)
Prss40	NP_033382.2	Tryp_SPc	68..308	CDD:214473	76/247 (31%)
		Tryp_SPc	69..311	CDD:238113	78/248 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	312..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6460
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950