DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	254	Identity:	90/254 - (35%)
Similarity:	124/254 - (48%)	Gaps:	27/254 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLALDFLSAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEE 73
            |::|..|..|:..: ..|::||....::..|||||:||...|||||||...:.|:||||||
Mouse   186 LVSLRCLDCGKSLK-TPRVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCF---- 245

  Fly    74 GNRLDDQGYQVRAGSALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPI-- 136
            ...||...::|||||.:. .|...:.||.:.|.|.........|||:|:|..||.|:..|:||
Mouse   246 RKYLDVSSWKVRAGSNIL-GNSPSLPVAKIFIAEPNPLYPKEKDIALVKLQMPLTFSGSVRPICL 309

  Fly   137 PLAKTNPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRLFD-------PSLLCA 194
            |.:.....|.:...|.|||  :...:...:....||.....|.|. .|...|       ..:|||
Mouse   310 PFSDEVLVPATPVWVIGWG--FTEENGGKMSDMLLQASVQVIDST-RCNAEDAYEGEVTAEMLCA 371

  Fly   195 GT--YGRTACHGDSGGPLVVNK---QLVGVVSWGRKGC---VSSAFFVSVPYFREWILN 245
            ||  .|:..|.|||||||:.:.   |:||:||||. ||   .:...:..|..:..||.|
Mouse   372 GTPQGGKDTCQGDSGGPLMYHSDKWQVVGIVSWGH-GCGGPSTPGVYTKVTAYLNWIYN 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	83/233 (36%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	82/232 (35%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335	3/8 (38%)
		Tryp_SPc	202..427	CDD:214473	83/233 (36%)
		Tryp_SPc	203..430	CDD:238113	85/236 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910