DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Hpn

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001263198.1	Gene:	Hpn / 15451	MGIID:	1196620	Length:	445	Species:	Mus musculus

Alignment Length:	255	Identity:	95/255 - (37%)
Similarity:	125/255 - (49%)	Gaps:	45/255 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGS-A 89
            ||:||:...:.:.||||||:|.|.|:||||:.|.:.::||||||  .|.||:..: ::|.||: |
Mouse   190 RIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCF--PERNRVLSR-WRVFAGAVA 251

  Fly    90 LTDSNGTLVDVAALIIHEEY------AFDLNINDIAIVRLSTPLEFTSKVQPI--PLAKTNPYPR 146
            .|..:...:.|.|:|.|..|      ..|.|.||||:|.||:.|..|..:||:  |.|.......
Mouse   252 RTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDG 316

  Fly   147 SIALVSGWGVSYILNDSTNLYPTH---LQGLALHIKSIFSCRLFD-------PSLLCAGTY---G 198
            .:..|:|||       :|..|...   ||...:.|.|...|...|       |.:.||| |   |
Mouse   317 KVCTVTGWG-------NTQFYGQQAMVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAG-YPEGG 373

  Fly   199 RTACHGDSGGPLVVNK--------QLVGVVSWGRKGCV---SSAFFVSVPYFREWILNAI 247
            ..||.||||||.|...        :|.|:|||| .||.   ....:..|..|||||..||
Mouse   374 IDACQGDSGGPFVCEDSISGTSRWRLCGIVSWG-TGCALARKPGVYTKVTDFREWIFKAI 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	91/249 (37%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	90/248 (36%)
Hpn	NP_001263198.1	Hepsin-SRCR	78..187	CDD:255261
		Tryp_SPc	190..428	CDD:214473	91/249 (37%)
		Tryp_SPc	191..428	CDD:238113	90/248 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910