DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and AgaP_AGAP003748

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_310280.7	Gene:	AgaP_AGAP003748 / 1271480	VectorBaseID:	AGAP003748	Length:	547	Species:	Anopheles gambiae

Alignment Length:	310	Identity:	81/310 - (26%)
Similarity:	126/310 - (40%)	Gaps:	83/310 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IESFLLLLA---------LDFLSAGQVNRWEQR-------------IIGGEPIGIEQVPWQVSLQ 45
            |.|.|||:|         :|....|..:....|             |.||....:::.|...::.
Mosquito     8 IASALLLIADLVFSENAFIDSAPEGYYDHCPSRFYSEDVSSALGFFIFGGRRAFLKEFPHMAAIG 72

  Fly    46 YFGDHV--------CGGSIYSENIIVTAAHCFFDEEGNRLDDQGY---------QVRAGS---AL 90
            :....|        ||||:.:...::|||||       ::||:.|         .||.|.   |.
Mosquito    73 WTDKTVSPPVVQYKCGGSLIAAKYVLTAAHC-------KVDDEKYVFIRVIPPDTVRLGDTNLAT 130

  Fly    91 TDSNGTL--VDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPI---PLAKTNPYPRSIAL 150
            |:.:.|.  ..:.:..:||::..:....|||::.|....:|.:.|.||   ||...:.|..|:..
Mosquito   131 TEDDETAQQFKIVSFAVHEKFKKNRKYYDIALIELDREAKFNTAVCPICLWPLDNIHEYSSSLRA 195

  Fly   151 VSGWG-VSYILNDSTNLYPTHLQGLALHIKSIFSC--------RL---FDPSLLCAGTYGRTACH 203
            : |:| .:|    ::.:.|| ||.::|:.....||        ||   ......|..|..:.||.
Mosquito   196 I-GFGFTTY----TSGMSPT-LQKVSLNYYDSDSCNNELPKDARLRYGLTSDQFCTKTPHKDACL 254

  Fly   204 GDSGGPLVVN--------KQLVGVVSWGRKGC--VSSAFFVSVPYFREWI 243
            |||||||.::        ..|.||||:| .||  .|...:..|..:..||
Mosquito   255 GDSGGPLQIDLSDVTRTIPYLTGVVSFG-TGCWDGSMGVYTKVASYINWI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	71/276 (26%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	70/262 (27%)
AgaP_AGAP003748	XP_310280.7	Tryp_SPc	54..305	CDD:238113	72/264 (27%)
		Tryp_SPc	54..303	CDD:214473	70/262 (27%)
		Trypsin	316..521	CDD:278516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910