DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17234 and KLK8

DIOPT Version :9

Sequence 1:NP_722785.1 Gene:CG17234 / 59225 FlyBaseID:FBgn0042187 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_653088.1 Gene:KLK8 / 11202 HGNCID:6369 Length:305 Species:Homo sapiens


Alignment Length:247 Identity:74/247 - (29%)
Similarity:106/247 - (42%) Gaps:23/247 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 SAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQ 80
            :||.....|.:::||........|||.:|......:|||.:...|.::|||||...:...||.|.
Human    67 AAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDH 131

  Fly    81 GYQVRAGSALTDSNGTLVDVAALIIHEEY----AFDLNINDIAIVRLSTPLEFTSKVQPIPLAKT 141
            ..|.:.|....      :.|...|.|..|    ..|.| :|:.:::|.......|||:||.||..
Human   132 SLQNKDGPEQE------IPVVQSIPHPCYNSSDVEDHN-HDLMLLQLRDQASLGSKVKPISLADH 189

  Fly   142 NPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRLFDP-----SLLCAG-TYGRT 200
            ...|.....|||||.  :.:...| :|..|....:.|.....|....|     .::||| :.|..
Human   190 CTQPGQKCTVSGWGT--VTSPREN-FPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGAD 251

  Fly   201 ACHGDSGGPLVVNKQLVGVVSWGRKGCVSS---AFFVSVPYFREWILNAIAS 249
            .|.||||||||.:..|.|:.|||...|..|   ..:.::..:.:||...|.|
Human   252 TCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17234NP_722785.1 Tryp_SPc 26..243 CDD:214473 67/229 (29%)
Tryp_SPc 27..243 CDD:238113 67/228 (29%)
KLK8NP_653088.1 Tryp_SPc 77..297 CDD:214473 67/229 (29%)
Tryp_SPc 78..300 CDD:238113 69/231 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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