DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	266	Identity:	85/266 - (31%)
Similarity:	129/266 - (48%)	Gaps:	48/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLLALDFLSAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDE 72
            |:::|..:..|.....|.||:||....|...||||:|||...::||||:.:.|.|||||||.
Frog   242 LVVSLKCIDCGLSTYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCV--- 303

  Fly    73 EGNRLDDQGYQVRAGS----ALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKV 133
            :|:......::...|.    :..||:...||  .:|:|.:|:...|.||||:::|.|.:.|:|..
Frog   304 QGDTSSPSLWKAFIGKIKMPSYYDSSAYSVD--RIIVHPDYSSQTNSNDIALMKLKTSIAFSSIS 366

  Fly   134 QPIPL-------AKTNPYPRSIALVSGWG-------VSYILNDS--TNLYPTHLQGLALHIKSIF 182
            :|:.|       .:..|     ..:||||       :|.:|..:  ..:.||......::..:|.
Frog   367 RPVCLPNYGMQWEEGQP-----CYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAIT 426

  Fly   183 SCRLFDPSLLCAGTY---GRTACHGDSGGPLVVNKQ----LVGVVSWGRKGCVS---SAFFVSVP 237
            |      |::||| |   |..:|.||||||||....    |||..||| .||.:   ...:.::.
Frog   427 S------SMICAG-YPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWG-DGCANVYRPGVYGNMT 483

  Fly   238 YFREWI 243
            .|.:||
Frog   484 VFLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	79/246 (32%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	78/245 (32%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	3/12 (25%)
		Tryp_SPc	261..489	CDD:238113	78/245 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910