Protein Alignment CG17239 and ACR

DIOPT Version :10

• Sequence 1: NP_722784.1
• Gene: CG17239 / 59224
• FlyBaseID: FBgn0042186
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 86/282 - (30%)
• Similarity: 128/282 - (45%)
• Gaps: 47/282 - (16%)

  Fly     6 IFLAFSVTVVSSN-------------WIPE---RIVGGDLITILSVPWQASI----LRLGRFH-C 49
            |.|..:|:||:.:             ..|:   |||||......:.||..|:    ....|:| |
Human     9 ILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTC 73

  Fly    50 GAAIYSEDIVITAAHCLTDRET--EFLSVRVGSSFTFFGGQVVR-------VSSVLLHEEYDQSW 105
            |.::.:...|:|||||...:..  ::..|......|:...:.|:       |..:::||:|:.:.
Human    74 GGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSAT 138

  Fly   106 -SNDIAVMRLQSKLRLGSAV--SVIP--LADTPPASGSPATVSGWGAIGFKKNYPMSIL-SASVD 164
             .||||::.:...:..|..:  ..:|  .|..|..|.| ..|:|||.|..|...|.||| .|.||
Human   139 EGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQS-CWVAGWGYIEEKAPRPSSILMEARVD 202

  Fly   165 IVDQDQCRRS--YGRKITKDMICAAAP-GK-DACSGDSGGPLV------SGNKLVGIVSFGKECA 219
            ::|.|.|..:  |..::....:||..| || |.|.|||||||:      |...:|||.|:|..||
Human   203 LIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCA 267

  Fly   220 HPEYPGVYANVAELKPWILGAI 241
            ..:.||:|........||...|
Human   268 RAKRPGIYTATWPYLNWIASKI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17239	NP_722784.1	Tryp_SPc	24..237	CDD:238113	76/242 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	77/243 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421