Protein Alignment CG17239 and KLK2

DIOPT Version :10

• Sequence 1: NP_722784.1
• Gene: CG17239 / 59224
• FlyBaseID: FBgn0042186
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 93/262 - (35%)
• Similarity: 128/262 - (48%)
• Gaps: 31/262 - (11%)

  Fly     5 W-IFLAFSVTVVSSNWIP---ERIVGGDLITILSVPWQASILRLGRFHCGAAIYSEDIVITAAHC 65
            | :.|:.:::|..:..:|   .|||||......|.|||.::...|..|||..:.....|:|||||
Human     2 WDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC 66

  Fly    66 LTDRETEFLSVRVGSSFTF---FGGQVVRVS----------SVLLHEEY--DQSWSNDIAVMRLQ 115
            |....    .|.:|....|   ..||.|.||          |:|.|:..  |:..|:|:.::||.
Human    67 LKKNS----QVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127

  Fly   116 SKLRLGSAVSVIPLADTPPASGSPATVSGWGAI---GFKKNYPMSILSASVDIVDQDQCRRSYGR 177
            ...::...|.|:.|....||.|:....||||:|   .|.:  |.|:...|:.::..|.|.|:|..
Human   128 EPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLR--PRSLQCVSLHLLSNDMCARAYSE 190

  Fly   178 KITKDMICAA--APGKDACSGDSGGPLVSGNKLVGIVSFGKE-CAHPEYPGVYANVAELKPWILG 239
            |:|:.|:||.  ..|||.|.||||||||....|.||.|:|.| ||.||.|.||..|...:.||..
Human   191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255

  Fly   240 AI 241
            .|
Human   256 TI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17239	NP_722784.1	Tryp_SPc	24..237	CDD:238113	85/233 (36%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	87/236 (37%)