DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17239 and KLK3

DIOPT Version :9

Sequence 1:NP_001259920.1 Gene:CG17239 / 59224 FlyBaseID:FBgn0042186 Length:248 Species:Drosophila melanogaster
Sequence 2:NP_001639.1 Gene:KLK3 / 354 HGNCID:6364 Length:261 Species:Homo sapiens


Alignment Length:261 Identity:92/261 - (35%)
Similarity:127/261 - (48%) Gaps:24/261 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MFVQWIFLAFSVT-VVSSNWIPERIVGGDLITILSVPWQASILRLGRFHCGAAIYSEDIVITAAH 64
            |:|..:||..||| :.::..|..|||||......|.|||..:...||..||..:.....|:||||
Human     1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65

  Fly    65 CLTDRETEFLSVRVGSSFTFF---GGQVVRVSSVLLHEEYDQSW------------SNDIAVMRL 114
            |:.::..    :.:|....|.   .|||.:||....|..||.|.            |:|:.::||
Human    66 CIRNKSV----ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRL 126

  Fly   115 QSKLRLGSAVSVIPLADTPPASGSPATVSGWGAIGFKKNY-PMSILSASVDIVDQDQCRRSYGRK 178
            .....|..||.|:.|....||.|:....||||:|..::.. |..:....:.::..|.|.:.:.:|
Human   127 SEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 191

  Fly   179 ITKDMICAA--APGKDACSGDSGGPLVSGNKLVGIVSFGKE-CAHPEYPGVYANVAELKPWILGA 240
            :||.|:||.  ..||..||||||||||....|.||.|:|.| ||.||.|.:|..|...:.||...
Human   192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256

  Fly   241 I 241
            |
Human   257 I 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17239NP_001259920.1 Tryp_SPc 23..237 CDD:214473 81/232 (35%)
Tryp_SPc 24..237 CDD:238113 80/231 (35%)
KLK3NP_001639.1 Tryp_SPc 25..256 CDD:238113 82/234 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8473
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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