DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17239 and Prss53

DIOPT Version :9

Sequence 1:	NP_001259920.1	Gene:	CG17239 / 59224	FlyBaseID:	FBgn0042186	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	221	Identity:	67/221 - (30%)
Similarity:	99/221 - (44%)	Gaps:	32/221 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PWQASILRLGRFHCGAAIYSEDIVITAAHCLTDRET-EFLSVRVGSSFTFFGGQVVRVSSVLLHE 99
            ||.|.:...|:..||.|:.||.:|:|||||...|:| |..||.:|:     |.:...:..::||.
Mouse   313 PWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEEWSVGLGA-----GPEEWGLKQLILHG 372

  Fly   100 EYDQ-SWSNDIAVMRLQSKLRLGSAVS--VIPLADTPPASGSPATVSGWGAIGFKK----NYPMS 157
            .|.. ....|:|.:.|...:.||..:.  .:|.||.....|.    .|| .:|..:    |||.:
Mouse   373 AYTHPEGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGE----HGW-VLGLTQKAGINYPQT 432

  Fly   158 ILSASVDIVDQDQCRRSY------GRKITKDMICAAAPGKDA-CSGDSGGPLVSGNK----LVGI 211
            :   .|.::....|.|.:      |..|...|:|....|:.. |.|.||.|||...:    |||:
Mouse   433 V---PVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGL 494

  Fly   212 VSFGKECAHPEYPGVYANVAELKPWI 237
            .|||..|.....|.|:|.::..:.||
Mouse   495 HSFGDTCQSSAKPAVFAALSAYEDWI 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17239	NP_001259920.1	Tryp_SPc	23..237	CDD:214473	65/219 (30%)
CG17239	NP_001259920.1	Tryp_SPc	24..237	CDD:238113	65/219 (30%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113
		Tryp_SPc	311..522	CDD:238113	67/221 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030