Protein Alignment CG17239 and PRSS36

DIOPT Version :10

• Sequence 1: NP_722784.1
• Gene: CG17239 / 59224
• FlyBaseID: FBgn0042186
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_775773.2
• Gene: PRSS36 / 146547
• HGNCID: 26906
• Length: 855
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 81/261 - (31%)
• Similarity: 118/261 - (45%)
• Gaps: 40/261 - (15%)

  Fly    21 PE---RIVGGDLITILSVPWQASILRLGRFHCGAAIYSEDIVITAAHCLTDRET-----EFLSVR 77
            ||   |||||......:.|||.|:...|...||.::.:...|::||||.....|     |: ||.
Human    41 PEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEW-SVL 104

  Fly    78 VG---SSFTFFGGQVVRVSSVLLHEEYDQ-SWSNDIAVMRLQSKLRLGSAVSVIPLADTPPAS-- 136
            :|   ......|.....|:::::...|.| ....|:|::||.|...||.||..:.|   |.||
Human   105 LGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCL---PRASHR 166

  Fly   137 ---GSPATVSGWGAIGFKKNYPMSILSASVD--IVDQDQCRRSYGR--------KITKDMICAAA 188
               |:....:|||.:......|:..:...|:  ::.:..|:..|.:        :|...|:||..
Human   167 FVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGY 231

  Fly   189 P--GKDACSGDSGGPLV--SGNK--LVGIVSFGKECAHPEYPGVYANVAELKPWILGAIERITKS 247
            |  .:|.|.||||||||  .|.:  ..||.|||..|.....|||:..||..:.||.   |::..|
Human   232 PEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIR---EQVMGS 293

  Fly   248 E 248
            |
Human   294 E 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17239	NP_722784.1	Tryp_SPc	24..237	CDD:238113	73/242 (30%)
PRSS36	NP_775773.2	Tryp_SPc	47..289	CDD:238113	75/248 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..316		2/3 (67%)
		Tryp_SPc	330..538	CDD:473915
		Tryp_SPc	601..783	CDD:473915