Protein Alignment CG17239 and KLK8

DIOPT Version :10

• Sequence 1: NP_722784.1
• Gene: CG17239 / 59224
• FlyBaseID: FBgn0042186
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 83/241 - (34%)
• Similarity: 124/241 - (51%)
• Gaps: 24/241 - (9%)

  Fly    17 SNWIP----------ERIVGGDLITILSVPWQASILRLGRFHCGAAIYSEDIVITAAHCLTDRET 71
            ||.:|          ::::||......|.||||::.:..:..||..:...:.|:|||||...:.|
Human    61 SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYT 125

  Fly    72 EFLSVRVGS-SFTFFGG--QVVRVSSVLLHEEYDQS----WSNDIAVMRLQSKLRLGSAVSVIPL 129
                ||:|. |.....|  |.:.|...:.|..|:.|    .::|:.:::|:.:..|||.|..|.|
Human   126 ----VRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL 186

  Fly   130 ADTPPASGSPATVSGWGAI-GFKKNYPMSILSASVDIVDQDQCRRSYGRKITKDMICA-AAPGKD 192
            ||.....|...||||||.: ..::|:|.::..|.|.|..|.:|..:|..:||..|:|| ::.|.|
Human   187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGAD 251

  Fly   193 ACSGDSGGPLVSGNKLVGIVSFGKE-CAHPEYPGVYANVAELKPWI 237
            .|.||||||||....|.||.|:|.: |...:.||||.|:.....||
Human   252 TCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17239	NP_722784.1	Tryp_SPc	24..237	CDD:238113	78/222 (35%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	78/223 (35%)