Protein Alignment MCU and mcu-1

DIOPT Version :10

• Sequence 1: NP_001246647.1
• Gene: MCU / 59223
• FlyBaseID: FBgn0042185
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_500892.1
• Gene: mcu-1 / 177362
• WormBaseID: WBGene00019296
• Length: 333
• Species: Caenorhabditis elegans
• Alignment Length: 272
• Identity: 113/272 - (41%)
• Similarity: 161/272 - (59%)
• Gaps: 5/272 - (1%)

  Fly   165 IYVEYVNGMPHMTVRLPSRNELCQFALKPISHNVGDLLAMLRAEDRGIDRAAVINKHGVRIASSC 229
            |..||  |:|.:.|.||||||.|||.::|:|..:|.|...||.||||||..||...:||::|:..
 Worm    53 IRFEY--GLPLLDVPLPSRNEPCQFTMRPLSDTIGSLCEFLRQEDRGIDYVAVYGTNGVKLATCT 115

  Fly   230 TIESLLD-DSFSIQINNRTLDVNPPKRDKVTLES--MDKVGDVRKVIAQLYEAFNVGEYQLEKSN 291
            :||.||. .||.:::|::..||..||...:..:|  :.::.|:|..:|.|:.|..|.||:|.:..
 Worm   116 SIEHLLQFGSFRLRLNDKFFDVTVPKTGTMPYDSDKLRQLDDLRATVASLHAALCVDEYKLSREK 180

  Fly   292 QLAKELETLRYELEPLEEKKLELSKKAARRTNFMTWMGLGLMSVQFGILARLTWWEYSWDIMEPV 356
            :|..:||.....|.||.:.|.::.::....|:.:.|.|...|.||.|:.||||||||||||||||
 Worm   181 KLLLQLENAETLLAPLHDAKRKIEQECEAHTDRVMWAGFAAMGVQTGLFARLTWWEYSWDIMEPV 245

  Fly   357 TYFVTYGTTMAMYAYYCVTKREYMMEDVKNREFSLSLYRNAKKVQFDVEHYNELKRKSAELEYNL 421
            |||.||.|..|.:.||..|::.:.....:.|.::...||.|:|..||:|.||.|..:..||...|
 Worm   246 TYFATYSTVCATFGYYLYTQQSFEYPSARERVYTKQFYRRAQKQNFDIEKYNRLVTEVDELRNQL 310

  Fly   422 RRINDPLNMQLP 433
            :|:.|||...||
 Worm   311 KRMRDPLFQHLP 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MCU	NP_001246647.1	MCU	208..410	CDD:461389	82/204 (40%)
mcu-1	NP_500892.1	MCU	94..299	CDD:461389	82/204 (40%)