DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt305A1 and UGT85A4

DIOPT Version :9

Sequence 1:	NP_001261394.1	Gene:	Ugt305A1 / 59217	FlyBaseID:	FBgn0042179	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_177950.1	Gene:	UGT85A4 / 844162	AraportID:	AT1G78270	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	100/553 - (18%)
Similarity:	199/553 - (35%)	Gaps:	158/553 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SLEAANILCLVSTAK-HNNPGWSKPLFDALLANGHSLLVIST--------------APNPEPKKQ 67
            |.:..:.:|:...|: |.||  ...|...|.|.|..:..::|              |.|..|..:
plant     8 SSQKPHAMCIPYPAQGHINP--MLKLAKLLHARGFHVTFVNTDYNHRRILQSRGPHALNGLPSFR 70

  Fly    68 V----DGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKR 128
            .    |||.:..:..:.|::|   |::.        |:|..|..::.|:    ..|||   .|..
plant    71 FETIPDGLPWTDVDAKQDMLK---LIDS--------TINNCLAPFKDLI----LRLNS---GSDI 117

  Fly   129 PELTAQLSMEYDLIITDVTQGI------ECLMDSVSGWRSKP---VLGLSAGKL----------T 174
            |.::.        ||:|.:...      |..:..|..|.:..   :|.|...||          :
plant   118 PPVSC--------IISDASMSFTIDAAEELKIPVVLLWTNSATALILYLHYQKLIEKEIIPLKDS 174

  Fly   175 PDLMSLLRAE-------NTINAARIPHYISQV-PKTMGFWNRLHNHIMYYAEPLIHLVITRPVLS 231
            .||...|..|       ..|.....|.:::.. |:                :|:|..::  .|..
plant   175 SDLKKHLETEIDWIPSMKKIKLKDFPDFVTTTNPQ----------------DPMISFIL--HVTG 221

  Fly   232 ELMKTE----NAFPKLQLVLLNTHPTLDYVQNLPPGVIEVG-------------------GLHIK 273
            .:.:..    |.|.||:      |..|..:::|.|.:..||                   ||::.
plant   222 RIKRASAIFINTFEKLE------HNVLLSLRSLLPQIYSVGPFQILENREIDKNSEIRKLGLNLW 280

  Fly   274 NQTSPLPTYIQEFTEKFFDGIVYINMPYIEYM-NDQGLKAMYTMIHGNPNVAFIWNVE------Q 331
            .:.:....::....||   .::|:|...:..: ::|.|:..:.:......  |:|.|.      .
plant   281 EEETESLDWLDTKAEK---AVIYVNFGSLTVLTSEQILEFAWGLARSGKE--FLWVVRSGMVDGD 340

  Fly   332 LEQLPAKKPNLLTLHVNQSL-------QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLK 389
            ...|||:   .|:...|:.:       |:.:|:...:.|||.|....|..|:::.|||::..|..
plant   341 DSILPAE---FLSETKNRGMLIKGWCSQEKVLSHPAIGGFLTHCGWNSTLESLYAGVPMICWPFF 402

  Fly   390 LEEFNNAQRVMERNLGVMLQV-KEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELA 453
            .::..|.:...| :.|:.::: :|..:..:...:..::|.|:. ..|.:..:::|...:.|
plant   403 ADQLTNRKFCCE-DWGIGMEIGEEVKRERVETVVKELMDGEKG-KRLREKVVEWRRLAEEA---- 461

  Fly   454 VWHAEQLIAEPRLFKHFAQTETLAQNFFVANSL 486
                    :.|.|...:...||:.......:::
plant   462 --------SAPPLGSSYVNFETVVNKVLTCHTI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	45/252 (18%)
UGT85A4	NP_177950.1	Glycosyltransferase_GTB-type	5..480	CDD:415824	100/545 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050