Protein Alignment Ugt305A1 and Ugt2b35

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 134/603 - (22%)
• Similarity: 238/603 - (39%)
• Gaps: 154/603 - (25%)

  Fly     3 ALCLLPVFVLLGRFC--SLEAANILCLVSTAKHNNPGWS--KPLFDALLANGHSLLVI--STAPN 61
            ||.||.:     .||  |.....:|.......|    |.  |.:.:.|:..||.:.|:  |.:..
  Rat     8 ALLLLQI-----SFCFKSGNCGKVLVWPMEYSH----WMNIKIILEELVQKGHEVTVLRPSASVF 63

  Fly    62 PEPKKQVDGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVW-YEVLLGSCRA--LLNSDT 123
            .:||:..| |.:...|..:   ..|.|......:::        || ||:...:|.:  |...||
  Rat    64 LDPKETSD-LKFVTFPTSF---SSHDLENFFTRFVN--------VWTYELPRDTCLSYFLYLQDT 116

  Fly   124 MS--------------SKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLT 174
            :.              |.:..:|.....::|::.:|                   .:| ..|:|.
  Rat   117 IDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSD-------------------AIG-PCGELI 161

  Fly   175 PDLMSL-----LR------AENTINA-----ARIPHYISQVPKTMGFWNRLHNHI--MYYA---- 217
            .:|:.:     ||      .|..|..     :.:|...|.:...|.|..|:||.|  :|:.
  Rat   162 AELLQIPFLYSLRFSPGYTIEKYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQ 226

  Fly   218 -------EPLIHLVITRP-VLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKN 274
                   :|.....:.|| .|:|:|      .|.::.|:.::..|::...:.|.|..:||||.|
  Rat   227 TFREKKWDPFYSKTLGRPTTLAEIM------GKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCK- 284

  Fly   275 QTSPLPTYIQEFTEKFFD-GIVYINMPYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQ---- 334
            ...|||..|::|.:...: |:|..::.          ..:..|.....|: ..|.:.|:.|
  Rat   285 PAKPLPKDIEDFVQSSGEHGVVVFSLG----------SMVRNMTEEKANI-IAWALAQIPQKVLW 338

  Fly   335 -LPAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEF 393
             ...|||.  ||..|..|     |.|:|.....|.|:.||.:..:.||||:|:|::.:||..|:.
  Rat   339 RFDGKKPP--TLGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQH 401

  Fly   394 NNAQRVMERNLGVMLQVKEFNQSSLSDALTRILD------EERFISALHQAQLKFRTRPQSALEL 452
            :|...::.:...|.:..:..::|.:.:||..:::      ...::|.:|..|      |...|:.
  Rat   402 DNIAHMVAKGAAVEVNFRTMSKSDMLNALEEVINNPFYKKNAMWLSTIHHDQ------PTKPLDR 460

  Fly   453 AVWHAEQLIAEPRLFKHFAQTETLAQN--FFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGS 515
            ||:..| .:...:..||.   .:|..|  ::..:||||:.. |:..:|..|.||...::.
  Rat   461 AVFWIE-FVMRHKGAKHL---RSLGHNLPWYQYHSLDVIGF-LLTCVAVTVVLALKCFLF----- 515

  Fly   516 KRQQTLEKAVLKKRKKSK 533
                 :.:..:||.||:|
  Rat   516 -----VYRFFVKKEKKTK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	58/235 (25%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	125/579 (22%)
		egt	<270..489	CDD:223071	59/242 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940