Protein Alignment Ugt305A1 and ugt2a6

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 581
• Identity: 127/581 - (21%)
• Similarity: 226/581 - (38%)
• Gaps: 128/581 - (22%)

  Fly    24 ILCLVSTAKHNNPGWS----------------KPLFDALLANGHSLLVISTAPNPE-PKKQVDGL 71
            :||.|..      |||                :|:.:||:...||:.|:..:.:|. |..|.:..
Zfish    11 LLCGVDV------GWSGRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERF 69

  Fly    72 VYYHLPNEYDVMKRHFLLEEPREYISM----VTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELT 132
                   ||.|.|.: :.:|..:|:.:    :.:|:.:..||..|...:.:   ....:...||.
Zfish    70 -------EYHVFKVN-MEKEVVDYLWIHFHELWMNETISTYEKTLEVWQLM---SLFRAHSEELV 123

  Fly   133 AQL----------SMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLT-PDLMSL------ 180
            ..|          ...||::.:|:|.               |...|.|.||. |.::|:
Zfish   124 KGLFDVGLLKTLRDSNYDVLFSDLTM---------------PFSDLMAQKLNIPHVLSMRISFAS 173

  Fly   181 ----LRAENTINAARIPHYISQ--VPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMKTENA 239
                |..:..:..:.:|..::|  :...|.|..|:.|.::|.....:..:.|:.....:....:.
Zfish   174 ALERLCGQMPVPQSYVPAAVAQGHLTDRMSFTERVENMLLYITHTAMFQLTTKFTFDHIYAEISG 238

  Fly   240 FP--------KLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFFD-GIV 295
            .|        |..:.|:.|:...:|.:..||....||||..| ...||...::||.:...| |||
Zfish   239 EPTTMCETIGKTDIWLIRTYWDFEYPRPFPPNFKFVGGLQCK-PAKPLAKELEEFVQSSGDHGIV 302

  Fly   296 YINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSL-----QQD 354
            ..:: ..|:.:..|....:...: |..:...:|      :...|.|.  ||..|..:     |.|
Zfish   303 VFSLGSMIKNLTVQKANTIAAAL-GQISQKVVW------RYSGKTPE--TLAPNTKIYDWIPQND 358

  Fly   355 ILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLS 419
            :|.....|.|:.||.:..|.|||::|||:|.|||..::.:|...:..:...|:|.........|.
Zfish   359 LLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLV 423

  Fly   420 DALTRILDEERF------ISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHF-AQTETLA 477
            |||..:|:...:      :|.:|..|      |...|:.||:..| .:...:..||. .|...|
Zfish   424 DALKTVLNNPSYKESIMRLSRIHHDQ------PMKPLDQAVYWIE-FVMRNKGAKHLRVQAHEL- 480

  Fly   478 QNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKSSPQ 538
             :::..:.|||        .|.::|:..|:..|:.   |....|.:..::|.:..:||..:
Zfish   481 -SWYQYHCLDV--------AAFLLSITALITFLWV---KACCFLFRRCVRKTRPERKSKKE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	111/500 (22%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	118/553 (21%)