Protein Alignment Ugt305A1 and Ugt2a3

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 602
• Identity: 127/602 - (21%)
• Similarity: 237/602 - (39%)
• Gaps: 156/602 - (25%)

  Fly     5 CLLPVFVL------LGRFCSLEAANILCLVSTAKHNNPGW--SKPLFDALLANGHSLLVISTAPN 61
            |:...|:|      .| |||    .:|.......|    |  .|.:.:.|.|.||.:.|:.
Mouse     6 CVAAFFLLQLCWAGCG-FCS----KVLVWPCDMSH----WLNLKTILEELGARGHEVTVLK---- 57

  Fly    62 PEPKKQVD-----GLVYYHLPNEYDVMKRHFLLEEPREYISMVTLN---QLLVW----------- 107
             .|...:|     .|.:.::|..|::......|.|    |:.:.:|   .|.:|
Mouse    58 -YPSIIIDQSKRIPLHFENIPLLYEIETAENRLNE----IANLAVNVIPNLSLWEAAKTLQDFFL 117

  Fly   108 -----YEVLLGSCRALL-NSDTMSSKRPELTAQLSMEYDLIITDVTQGIEC-------------- 152
                 :|.:   ||::| |...|...|       ..:||:::.|..  :.|
Mouse   118 QVTGDFESI---CRSVLYNQKFMDKLR-------DAQYDVVVIDPV--VPCGELVAEVLQIPFVY 170

  Fly   153 -LMDSVSGWRSK------------PVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMG 204
             |..|:..:..|            ||:   ..:||.::....|.:|.:.:....:::.|.  ...
Mouse   171 TLRFSMGYYMEKHCGQLPIPLSYVPVV---MSELTDNMTFTERVKNMMFSLLFEYWLQQY--DFA 230

  Fly   205 FWNRLHNHIMYYAEPLIHLVITRPVLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGG 269
            ||::      :|:|.|     .||  :...||..   |..:.|:.|:..:::.:...|....|||
Mouse   231 FWDQ------FYSETL-----GRP--TTFCKTVG---KADIWLIRTYWDVEFPRPYLPNFEFVGG 279

  Fly   270 LHIKNQTSPLPTYIQEFTEKFFD-GIVYINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQL 332
            ||.| ...|||..::||.:...: |:|..:: ..::.:.::....:.:::...|. ..:|
Mouse   280 LHCK-PAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANLIASVLAQIPQ-KVLW----- 337

  Fly   333 EQLPAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEE 392
             :...|||  .||..|..|     |.|:|.....|.|:.||.:..:.|||::|||:|.:|:..::
Mouse   338 -RYSGKKP--ATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQ 399

  Fly   393 FNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALE 451
            .:|...:..:...:.:.:.....:.|..|:..:::|..:      :|.:|..|      |...|:
Mouse   400 PHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQ------PVKPLD 458

  Fly   452 LAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLV--YVLYTGG 514
            .||:..| .:...:..||. :......::|..:||||:.    .||..||:|..::  :.|:
Mouse   459 RAVFWIE-FVMRHKGAKHL-RVAAHDLSWFQYHSLDVIG----FLLLCVVTLTFIITKFCLF--- 514

  Fly   515 SKRQQTLEKAVLKKRKK 531
                 ..:|..:|:.||
Mouse   515 -----VCQKLYMKESKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	53/231 (23%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	118/576 (20%)
		egt	<268..507	CDD:223071	62/260 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840300
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030