Protein Alignment Ugt305A1 and Ugt8

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_062149.1
• Gene: Ugt8 / 50555
• RGDID: 3938
• Length: 541
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 126/634 - (19%)
• Similarity: 225/634 - (35%)
• Gaps: 160/634 - (25%)

  Fly     8 PVFVLLGRFCSL-EAANILCLVSTAKHNNPGWSKPLFDALLANG-HSLLVISTAPNPEPKKQVDG 70
            |.|:||.....: .||.|:.:......::....|.|..||...| |::.::|...:.:|.
  Rat     6 PYFMLLWSAVGIARAAKIIIVPPIMFESHLYIFKTLASALHERGHHTVFLLSEGRDIDPS----- 65

  Fly    71 LVYYHLPNEYDVMKRH-----------FLLEEPREYIS----MVTLNQLLVWYEVLLGSCRALLN 120
                   |.|. ::|:           ||..:.|...|    .|.|..:|..|         ..|
  Rat    66 -------NHYS-LQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAVELVDILDHY---------TKN 113

  Fly   121 SDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAEN 185
            .|.|...:..:......::||::.|        .:.:.|:....:||:.....:..|........
  Rat   114 CDMMVGNQALIQGLKKEKFDLLLVD--------PNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGA 170

  Fly   186 TINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMKTENAFPK-------- 242
            ....|.:|.:.|.:...|.|..|:.|..:|....:....:..|....:|:..|..|.
  Rat   171 PAPLAYVPEFNSLLTDRMNFLERMKNTGVYLISRMGVSFLVLPKYERIMQKYNLLPAKSMYDLVH 235

  Fly   243 -LQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFFD-GIVYINM-PYIEY 304
             ..|.:|.|...|::.:...|.|:.|||: :....||||..:|.:.:...: |.|.::. ..::|
  Rat   236 GSSLWMLCTDVALEFPRPTLPNVVYVGGI-LTKPASPLPEDLQRWVDGAQEHGFVLVSFGAGVKY 299

  Fly   305 MNDQGLKAMYTMIHGNPNVAFIW------------NVEQLEQLPAKKPNLLTLHVNQSLQQDILA 357
            :::.....:...:...|. ..||            |.:.:|.||               |.|:|.
  Rat   300 LSEDIANKLAGALGRLPQ-KVIWRFSGTKPKNLGNNTKLIEWLP---------------QNDLLG 348

  Fly   358 MQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDAL 422
            ...::.||:||...|:.|.:::|||||.:||..:.::...||..:.:|::|:.....:..|.|||
  Rat   349 HSNIRAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWNTVTEGELYDAL 413

  Fly   423 TRILDEERF------ISALHQAQ-----------LKFRTRPQSALELAVWHAEQLIAEPRLFKHF 470
            .::::...:      :|.:|:.|           :.:..|...|     .|....:.:....::|
  Rat   414 VKVINNPSYRQRAQKLSEIHKDQPGHPVNRTTYWIDYILRHDGA-----HHLRSAVHQISFCQYF 473

  Fly   471 AQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYV---LYTGGSKRQQTLEKAVLKKRKKS 532
                             :|.:..::||.||.....:.||   :|                 ||..
  Rat   474 -----------------LLDIAFVLLLGAVALYFIVSYVTKFIY-----------------RKVK 504

  Fly   533 KKSSPQTFTPVNVTLKLETSELLEDLNNEILEGEEELLKGEEKPLEEKK 581
            ...|..|.:.||           ....|.||.|.   .||......|||
  Rat   505 SLCSRSTHSTVN-----------GHYQNGILNGR---YKGNGHIKHEKK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	97/493 (20%)
Ugt8	NP_062149.1	Glycosyltransferase_GTB-type	21..502	CDD:471961	106/566 (19%)