Protein Alignment Ugt305A1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 588
• Identity: 134/588 - (22%)
• Similarity: 243/588 - (41%)
• Gaps: 126/588 - (21%)

  Fly     7 LPVFVLLG--RFCSL---EAANILCLVSTAKHNNPGW--SKPLFDALLANGHSLLVISTAPN--- 61
            :|:..|:|  ..|:|   |...:|.......|    |  .:.:...|.|.||..:|::...|
Mouse     5 MPLQGLVGLLLLCALPWTEGEKVLVFPVGGSH----WLSMRDVVRELHAQGHQTVVLAPEVNMRI 65

  Fly    62 -------------PEPKKQVDGL-----VYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWY 108
                         |..:::::.:     |::...|   .||:.|...|....:|
Mouse    66 KEEDFFTFKVYAVPYTRQELEEMMENLKVFFDTGN---YMKKIFKTSEALRNMS----------- 116

  Fly   109 EVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAG-- 171
            .|||.:|..:|:::::      |....|..:|::.||.......|:        ...||:.|.
Mouse   117 TVLLKTCTNILHNESL------LHHLNSSSFDVVFTDPVFPCGALL--------AKYLGIPAVFF 167

  Fly   172 -KLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYY--AEPLIHLVIT--RPVLS 231
             :..|..:.....:....::.||:..:::...|.|..|:.| ::|:  .:.:.||:||  ..:.|
Mouse   168 LRYIPCGIEYEATQCPSPSSYIPNLFTRLSDHMDFLQRVQN-MLYHLVLKYICHLLITPYESLAS 231

  Fly   232 ELMKTE----NAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFFD 292
            ||.:.|    ..|....:.|......|||.:.:.|.::.:||::...: .||.   |||.
Mouse   232 ELFQREVSSVELFSYASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK-KPLS---QEFE----- 287

  Fly   293 GIVYINMPYIEYMNDQGLK--AMYTMIHGNPNVAFIWNVEQLEQLP--------AKKPNLL---T 344
                   .|:....:.|:.  ::.:|:...|....:...|.|.::|        ..:|:.|   |
Mouse   288 -------AYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNT 345

  Fly   345 LHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQ 409
            :.|....|.|:|.....:.|:.|..|..:.|.|..|||:|::||..::.:||:|:..|..||.|.
Mouse   346 ILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLN 410

  Fly   410 VKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALELAVWHAEQLI---AEPR 465
            |.|.....|.:||..:::.:.:      :|:||      :.||...|:|||:..|.::   ..|.
Mouse   411 VLEMTADDLENALKTVINNKSYKENIMRLSSLH------KDRPIEPLDLAVFWVEYVMRHKGAPH 469

  Fly   466 LFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRK 530
            | :..|...|    ::..:||||:.    .|||.|:::..:|:.....|. |:....|..:||..
Mouse   470 L-RPAAHDLT----WYQYHSLDVIG----FLLAIVLTVVFIVFKCCAYGC-RKCFGGKGRVKKSH 524

  Fly   531 KSK 533
            |||
Mouse   525 KSK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	107/490 (22%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	123/558 (22%)