Protein Alignment Ugt305A1 and Ugt2b7

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_775445.2
• Gene: Ugt2b7 / 286989
• RGDID: 708417
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 583
• Identity: 131/583 - (22%)
• Similarity: 233/583 - (39%)
• Gaps: 147/583 - (25%)

  Fly     3 ALCLLPVFVLLGRFC--SLEAANILCLVSTAKHNNPGWS--KPLFDALLANGHSLLVI--STAPN 61
            ||.||.:     .||  |.....:|.......|    |.  |.:.|.|:..||.:.|:  |::..
  Rat     8 ALLLLQI-----SFCFRSGNCGKVLVWPLEYSH----WMNLKIILDELVQRGHEVTVLRPSSSVF 63

  Fly    62 PEPKKQVDGLVYYHLPN------------------EYDVMKRHFLLEEPREYISMVTLNQLL--- 105
            .:||| ..||||...|.                  .|||.|...|...|       :||::.
  Rat    64 LDPKK-ASGLVYETFPTTSNNDEVEKFFTQWVNTWTYDVPKYTCLRYYP-------SLNKMFGQF 120

  Fly   106 --VWYEVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGL 168
              :|.::    ||.::::..:.:|..|      .::|::::|...
  Rat   121 SDLWLQL----CREVVSNKHLMAKLKE------SQFDVVLSDAVG-------------------- 155

  Fly   169 SAGKLTPDLMSL-----LR-----------AENTINAARIPHYISQVPKTMGFWNRLHNH--IMY 215
            ..|:|..:::.|     ||           |......:.:|..:|.:...|.|..|:.|.  ::|
  Rat   156 PCGELIAEILQLPFVYSLRFGIGYGIEKYSAGQPFPPSYVPIILSGLSGQMTFMERVENMLCLLY 220

  Fly   216 YA-----------EPLIHLVITRP-VLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVG 268
            :.           :|....::.|| .:.:.||      |.::.|:.::..|::.:...|.:..||
  Rat   221 FDFWFESFPAKDWDPFFSEILGRPTTMVDTMK------KAEIWLIRSYWDLEFPRPSLPNIEFVG 279

  Fly   269 GLHIKNQTSPLPTYIQEFTEKFFD-GIVYINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQ 331
            |||.: ...|||..:::|.:...: |:|..:: ..|..:..:....:.:.:...|...| |..|
  Rat   280 GLHCQ-PAKPLPKEMEDFAQSSGEHGVVVFSLGSMIRNITQERANTIASALAQIPQKVF-WRFE- 341

  Fly   332 LEQLPAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLE 391
                 .|||:  ||..|..:     |.|:|.....|.|:.||.:..:.|:||:|:|:|.:||..|
  Rat   342 -----GKKPD--TLGPNTRVFKWIPQNDLLGHPKTKAFVTHGGANGIYESIHHGIPMVGIPLFAE 399

  Fly   392 EFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSAL 450
            :.:|...::.:...|.|.....:.|.|.:||..::::..:      :||:|..|      |...|
  Rat   400 QRDNVAHMVAKGAAVSLDFHTMSSSDLLNALKAVINKPSYKKKVMWLSAIHHDQ------PLKPL 458

  Fly   451 ELAVWHAEQLIAEPRLFKHFAQTETLAQN--FFVANSLDVLTVPLIVLLAAVVSLANLVYVLY 511
            :.||:..| .:...:..||.   ..||.|  ::..:||||:...|..:||.|:........||
  Rat   459 DRAVFWIE-FVMRHKGAKHL---RPLAHNLAWYQYHSLDVIGFLLACVLAIVLLAVKCCLFLY 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	109/507 (21%)
Ugt2b7	NP_775445.2	UDPGT	24..527	CDD:278624	124/562 (22%)