Protein Alignment Ugt305A1 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 135/601 - (22%)
• Similarity: 237/601 - (39%)
• Gaps: 157/601 - (26%)

  Fly     9 VFVLLGRFC--SLEAANILCLVSTAKHNNPGWS--KPLFDALLANGHSLLVISTAPNP----EPK 65
            :|:|...:|  |.....:|.......|    |.  |.:.|.|:..||.:.|:.  |:.    :||
  Rat     9 LFLLQISYCFKSGHCGKVLVWPMDFSH----WMNIKIILDELVQRGHEVTVLK--PSAYFFLDPK 67

  Fly    66 KQVD-GLVYYHLPNEYDVMKRHFL-------LEEPRE-YISMVTLNQLLVWYE---VLLGSCRAL 118
            |..| ....:......|.::.||:       .|.||: .:|...:.|.|| ||   ..|..|:
  Rat    68 KSSDLKFEIFSTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLV-YEFSYFYLSICK-- 129

  Fly   119 LNSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSL--- 180
               |.:|:|: .:|.....::|::..|                  ||  .|.|.|..:|:.:
  Rat   130 ---DAVSNKQ-LMTKLQESKFDVLFAD------------------PV--ASCGDLIAELLHIPFL 170

  Fly   181 --------LRAENTIN-----AARIPHYISQVPKTMGFWNRLHNHIM-----YYAEPLIHL---- 223
                    .:.|.:|.     .:.:|..:|.:...|.|.:|:.|.|.     ::.|.|.|.
  Rat   171 YSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFEILRHKEWDT 235

  Fly   224 ----VITRPVLSELMKTENAFPKLQLVLLNT-------HPTLDYVQNLPPGVIEVGGLHIKNQTS 277
                ::.||.     ..:....|:::.|:.:       ||||       |.|..:||||.| ...
  Rat   236 FYSEILGRPT-----TVDETMSKVEIWLIRSYWDLKFPHPTL-------PNVDYIGGLHCK-PAK 287

  Fly   278 PLPTYIQEFTEKFFD-GIVYINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQ-----L 335
            |||..::||.:...: |:|..:: ..:..|.::...|:            .|.:.|:.|     .
  Rat   288 PLPKDMEEFVQSSGEHGVVVFSLGSMVSNMTEEKANAI------------AWALAQIPQKVLWKF 340

  Fly   336 PAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNN 395
            ..|.|  .||..|..:     |.|||.....|.|:.||.:..|.|||::|:|::.:||..::.:|
  Rat   341 DGKTP--ATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDN 403

  Fly   396 AQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALELAV 454
            ...::.:...|.|.::..::.....||..::|...:      :|.:|..|      |...|:.||
  Rat   404 IAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQ------PMKPLDRAV 462

  Fly   455 WHAEQLIAEPRLFKHFAQTETLAQN--FFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKR 517
            :..| .|...:..||.   ..|..|  ::..:||||  :..::...||::...:..:|:
  Rat   463 FWIE-FIMRHKGAKHL---RPLGHNLPWYQYHSLDV--IGFLLTCFAVIAALTVKCLLF------ 515

  Fly   518 QQTLEKAVLKKRKKSK 533
               :.:..:||.||.|
  Rat   516 ---MYRFFVKKEKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	114/509 (22%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	129/583 (22%)