Protein Alignment Ugt305A1 and Ugt2b35

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 562
• Identity: 131/562 - (23%)
• Similarity: 220/562 - (39%)
• Gaps: 145/562 - (25%)

  Fly    40 KPLFDALLANGHSLLVI--STAPNPEPKKQVDGLVYYHLPNEY--DVMKR-------HFLLEEPR 93
            |.:.|.|:..||.:.|:  |.:...:||.. .||.:...|..:  |.::.       .:..|.||
Mouse    40 KIILDELVQRGHEVTVLRPSASIFVDPKYS-PGLKFETFPTAFSKDYLETFLTKLVDEWTFEVPR 103

  Fly    94 E----YISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLM 154
            :    |..:.||...|..|.:.|  |:..:::..:.:|..|      .::|::|.|..
Mouse   104 DTCLSYSLLQTLFGKLSDYSLSL--CKEAVSNKQLMTKFQE------SKFDVLILDAM------- 153

  Fly   155 DSVSGWRSKPVLGLSAGKLTPDLMSL-----LR-------AENTINAARIPHYISQVPKTMG--- 204
                         .|.|:|...|:.:     ||       .:|:......|.|:..:...:|
Mouse   154 -------------ASCGELIAQLLQIPFLYSLRFSPGYQVEKNSGGFVLPPSYVPVILSGLGGQM 205

  Fly   205 -FWNRLHNHI------------------MYYAEPLIHLVITRP-VLSELM-KTENAFPKLQLVLL 248
             |..|:.|.|                  .:|:|.|     .|| .|.|.| |.|..|.:....|.
Mouse   206 TFTERVKNMICMLYFDFWFQTFTEKEWDQFYSETL-----GRPTTLIETMGKAEMWFIRSYWDLE 265

  Fly   249 NTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKF-FDGIVYINM-PYIEYMNDQGLK 311
            ..||||       |.|..|||||.| ...|||..:::|.:.. ..|:|..:: ..:..|.::...
Mouse   266 FPHPTL-------PNVEYVGGLHCK-PAKPLPKEMEDFVQSSGVHGVVVFSLGSMVSNMTEERAN 322

  Fly   312 AMYTMIHGNPNVAFIWNVEQLEQ-----LPAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLN 366
            |:            .|.:.|:.|     ...|.|  .:|..|..:     |.|:|.....|.|:.
Mouse   323 AI------------SWALAQIPQKVLWRFDGKTP--ASLGPNTRIYKWLPQNDLLGHPKTKAFVT 373

  Fly   367 HGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERF 431
            ||.:..|.||||:|:|::.:||..|:.:|...::.:...|.|.::..::|.|.:||..:::...:
Mouse   374 HGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVALNIRTMSRSDLLNALEEVINNPSY 438

  Fly   432 ------ISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQN--FFVANSLDV 488
                  :|.:|..|      |...|...::..| .:...:..||.   ..||.|  ::..:||||
Mouse   439 KENVMWLSTIHHDQ------PMKPLNRTIFWIE-FVMRHKGAKHL---RPLAHNLTWYQYHSLDV 493

  Fly   489 LTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRK 530
            :...|:.::|..|........:|      |..::||  ||||
Mouse   494 IGFLLVCVVATAVLPVKCCLFVY------QFFVKKA--KKRK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	58/236 (25%)
Ugt2b35	NP_766469.1	egt	8..506	CDD:223071	122/531 (23%)
		UDPGT	24..525	CDD:278624	127/558 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030