Protein Alignment Ugt305A1 and Ugt2b36

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001025038.1
• Gene: Ugt2b36 / 231396
• MGIID: 3576103
• Length: 530
• Species: Mus musculus
• Alignment Length: 607
• Identity: 141/607 - (23%)
• Similarity: 245/607 - (40%)
• Gaps: 162/607 - (26%)

  Fly     3 ALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWS--KPLFDALLANGHSLLVI--STAPNPE 63
            ||.||.:...   |.|.:...:|.......|    |.  |.:.|.|...||.:.|:  ||:...:
Mouse     8 ALLLLQISCC---FRSAKCGKVLVWPVDYSH----WMNIKIILDELKQKGHEVTVLRPSTSIFLD 65

  Fly    64 PKKQVDGLVYYHLPNEY--DVMK-------RHFLLEEPREYISMVTLNQLL-----VWYEVLLGS 114
            |||. .||.:...|..:  |||:       ..:..|.||:  :.::.:.||     .:.:..|..
Mouse    66 PKKS-PGLKFETFPTSFSNDVMEIIFAKAVERWTYEVPRD--TCLSYSPLLQNIFDEYSDYCLTL 127

  Fly   115 CRALLNSDTMSSKRPELTAQL-SMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLM 178
            |:     ||:|:|  :|.|:| ..::|:|::|                   .:| ..|:|..:|:
Mouse   128 CK-----DTVSNK--QLMAKLQESKFDVILSD-------------------AIG-PCGELIAELL 165

  Fly   179 SL-----LRAEN-----------TINAARIPHYISQVPKTMGFWNRLHNHI-------------- 213
            .:     ||...           .:..:.:|..:|.:...|.|..|:.|.|
Mouse   166 QIPFLYSLRFSPGYYLEKYSGGLPLPPSYVPVILSGLSGQMTFKERVKNMICMLYFDFWFQTFRE 230

  Fly   214 ----MYYAEPLIHLVITRPVLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKN 274
                .:|:|.|     .||  :.|::|   ..|.::.|:.::..|::.....|.|..|||:|.|
Mouse   231 KKWDQFYSETL-----GRP--TTLIET---MGKAEMWLIRSYWDLEFPHPTLPNVYYVGGVHCK- 284

  Fly   275 QTSPLPTYIQEFTEKFFD-GIVYINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQ--- 334
            ...|||..:::|.:...: |:|..:: ..:..|.::...|:            .|.:.|:.|
Mouse   285 PAKPLPKEMEDFVQSSGEHGVVVFSLGSMVSNMTEEKANAI------------AWALAQIPQKVL 337

  Fly   335 --LPAKKPNLLTLHVNQSL-----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEE 392
              ...|.|  .||..|..:     |.|:|.....|.|:.||.:..|.||||:|:|::.:||..|:
Mouse   338 WRFDGKTP--ATLGPNTRIYKWLPQNDLLGHPKTKAFITHGGANGLYEAIHHGIPMIGIPLFGEQ 400

  Fly   393 FNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILD------EERFISALHQAQLKFRTRPQSALE 451
            .:|...::.:...|.|.::..::|.|.:||..::|      ...::|.:|..|      |...|:
Mouse   401 HDNIAHMVAKGAAVTLNIRTMSRSDLLNALEEVIDNPFYKENAMWLSTIHHDQ------PMKPLD 459

  Fly   452 LAVWHAEQLIAEPRLFKHFAQTETLAQN--FFVANSLDV---LTVPLIVLLAAVVSLANLVYVLY 511
            .||:..| .:...:..||.   ..||.|  ::..:||||   |...:..::|.:|.....||..:
Mouse   460 RAVFWIE-FVMRHKGAKHL---RPLAYNLTWYQYHSLDVIGFLLAFVTFIVALIVKCFLFVYRFF 520

  Fly   512 TGGSKRQQTLEKAVLKKRKKSK 533
                          :||.||.|
Mouse   521 --------------VKKEKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	59/236 (25%)
Ugt2b36	NP_001025038.1	egt	8..506	CDD:223071	132/569 (23%)
		UDPGT	24..527	CDD:278624	133/585 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940