Protein Alignment Ugt305A1 and Ugt3a1

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_659094.1
• Gene: Ugt3a1 / 223337
• MGIID: 2145969
• Length: 523
• Species: Mus musculus
• Alignment Length: 592
• Identity: 138/592 - (23%)
• Similarity: 231/592 - (39%)
• Gaps: 169/592 - (28%)

  Fly     6 LLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSL--LVISTAPNPEPKKQV 68
            ||..|:.| ....||||.|| .:||...::......:...|...||::  |:..:|..|:.:|:.
Mouse     8 LLMSFLFL-EVILLEAAKIL-TISTLSASHYIVISRVSQVLHEGGHNVTKLLYESANIPDFRKEK 70

  Fly    69 DG--LVYYHLPNEYD---VMKRHFLLEEPREYISMVTLNQ-----LLVWYEVLLGSCRALLN-SD 122
            ..  ::.:..|.:.:   ...||.|.||       :|..:     ||..::.....|..||: .|
Mouse    71 PSYQVINWRPPEDQEKKFADLRHRLTEE-------ITYGRSKHHTLLKIHQYFGDLCSQLLSRKD 128

  Fly   123 TMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAEN-- 185
            .|...:.|       .:||:          |:||:                  ||.|||..|.
Mouse   129 IMDFLKNE-------NFDLV----------LLDSM------------------DLCSLLIVEKLG 158

  Fly   186 -------------------TINAARIPHYISQVPKTMGFWNRLHNHIMY-------------YAE 218
                               :...:..|.|.|.:...|.||.|:.|.:|:             |..
Mouse   159 KRFVSFLPFQFSYMDFGLPSAPLSYAPVYGSGLTDQMDFWGRVKNFLMFLDFSMKQREILSQYDS 223

  Fly   219 PL-IHLVI-TRPVLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPT 281
            .: .|.|. ::||||:|:.      |.:|..:|:...||:.:.|.|..:.|||| :.....|:|.
Mouse   224 TIQEHFVEGSQPVLSDLLL------KAELWFVNSDFALDFARPLFPNTVYVGGL-LDKPVQPIPQ 281

  Fly   282 YIQEFTEKFFD-GIVYI----------NMPYIEYMND------QGLKAMYTMIHGNPNVAFIWNV 329
            .::.|..:|.| |.|.:          :...|:.||.      ||:.......|...:|:...||
Mouse   282 DLENFISQFGDSGFVLVALGSIVSMIQSKEIIKEMNSAFAHLPQGVLWTCKTSHWPKDVSLAPNV 346

  Fly   330 EQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFN 394
            :.::.||               |.|:||...::.|:.||...|:.||:|:|||:|.:|...::..
Mouse   347 KIMDWLP---------------QTDLLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFFDQPE 396

  Fly   395 NAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQ 459
            |..||..:||||.:|::.....|.:..:.:|::::|:.||...:::             :.|:..
Mouse   397 NMVRVEAKNLGVSIQLQTLKAESFALTMKKIIEDKRYKSAAMASKI-------------IRHSHP 448

  Fly   460 LIAEPRL---FKHFAQTETLA--------QNFFVANSLDV-------------LTVPLIVLLAAV 500
            |....||   ..|..||...|        |.:.....|||             |:|.::|.:...
Mouse   449 LTPAQRLLGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFLLGLMLGTLWLSVKVLVAVTRY 513

  Fly   501 VSLANLV 507
            :|:|..|
Mouse   514 LSIATKV 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	114/503 (23%)
Ugt3a1	NP_659094.1	Glycosyltransferase_GTB-type	23..488	CDD:471961	123/542 (23%)