Protein Alignment Ugt305A1 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 604
• Identity: 146/604 - (24%)
• Similarity: 252/604 - (41%)
• Gaps: 151/604 - (25%)

  Fly     4 LC--LLPVFVLLGRFCSL---EAANILCLVSTAKHNNPGW--SKPLFDALLANGHSLLVISTAPN 61
            ||  |..:..||...|:|   |.|.:|.|......    |  .:.:...|.|.||..:|:::
Mouse     5 LCVPLRGISGLLLLLCALPWAEGAKVLVLPMEGSQ----WLSMRDVVRELHARGHQTVVLAS--- 62

  Fly    62 PEPKKQVDG-----LVYYHLP---NEY------DVMK----RHFLLEEPREYISMVTLNQLLVWY 108
             |....:.|     |..|..|   .||      |:.|    :||:    :.:..  |...:..::
Mouse    63 -EVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFV----KAFFE--TTASIRNFF 120

  Fly   109 EVLLGSCRALLNSDTMSSKRPELTAQL-SMEYDLIITDVTQGIECLMDSVSGWRSKPVL---GLS 169
            ::...||.|||::..       |..|| |..:|:|:||                  |:.   .:.
Mouse   121 DLYSNSCIALLHNKM-------LIQQLNSSFFDVILTD------------------PIFPCGAVL 160

  Fly   170 AGKLTPDLMSLLR---------AENTIN-AARIPHYISQVPKTMGFWNRLHNHIMYY--AEPLIH 222
            |..|....:.:||         |....| ::.||:.::::...|.|..|:.| ::||  .:.:..
Mouse   161 AKYLQIPAVFILRSLSCGIEYEATQCPNPSSYIPNLLTRLSDHMDFLQRVQN-MLYYLVLKYICR 224

  Fly   223 LVIT--RPVLSELMKTENAFPKLQLVLLNTHPT---------LDYVQNLPPGVIEVGGLHIKNQT 276
            |.||  ..:.|||::.|     :.||.:.:|.:         |||.:.:.|.::.:||::...:
Mouse   225 LSITPYESLASELLQRE-----VSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK- 283

  Fly   277 SPLPTYIQEFTEKFFDGIVYINMPYIEYMNDQGLK--AMYTMIHGNPNVAFIWNVEQLEQLP--- 336
            .||.   |||.            .|:....:.|:.  ::.:|:...|....:...|.|.::|
Mouse   284 KPLS---QEFE------------AYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTV 333

  Fly   337 -----AKKPNLL---TLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEF 393
                 ..:|:.|   |:.|....|.|:|.....:.|:.|..|..:.|.|..|||:|::||..::.
Mouse   334 LWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQM 398

  Fly   394 NNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALEL 452
            :||:|:..|..||.|.|.|.....|.:||..:::.:.:      :|:||      :.||...|:|
Mouse   399 DNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLH------KDRPIEPLDL 457

  Fly   453 AVWHAEQLI---AEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGG 514
            ||:..|.::   ..|.| :..|...|    ::..:||||:.    .|||.|:::..:|:.....|
Mouse   458 AVFWVEYVMRHKGAPHL-RPAAHDLT----WYQYHSLDVIG----FLLAIVLTVVFIVFKCCAYG 513

  Fly   515 SKRQQTLEKAVLKKRKKSK 533
            . |:....|..:||..|||
Mouse   514 C-RKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	61/246 (25%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	133/572 (23%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	35/166 (21%)
		egt	<261..505	CDD:223071	70/274 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840