DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt305A1 and H23N18.4

DIOPT Version :9

Sequence 1:	NP_001261394.1	Gene:	Ugt305A1 / 59217	FlyBaseID:	FBgn0042179	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_504314.2	Gene:	H23N18.4 / 186769	WormBaseID:	WBGene00019235	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	459	Identity:	106/459 - (23%)
Similarity:	178/459 - (38%)	Gaps:	111/459 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NP--GWSKPLF-----DALLANGHSLLVISTAPNPEPKKQVDGLV---------YYHLPNEYDVM 83
            ||  |:|...|     |.:..:||::.:..  |.....|..|.||         ||  |:.||.:
Worm    25 NPIFGFSHVKFISKMADIIADHGHNVTLFQ--PFHLALKNADKLVKNQNIKIINYY--PDHYDEL 85

  Fly    84 ----KRHF-------LLEEPREYISMV----------TLNQLLVWYEVLLGSCRALLNS--DTMS 125
                |:.|       |:..|.....|:          |..|||...:|:    ..|.|.  |.:.
Worm    86 LKTEKKTFPMLWDSQLMNNPILCSFMMPNIMEDSWEKTATQLLKDQKVI----EDLKNQKFDVVL 146

  Fly   126 SKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAA 190
            |:..|||. :.:.|.|.|.::                 |:  :||.:..| ........:|:  .
Worm   147 SETFELTG-IYLAYLLEIPNI-----------------PI--MSAVRFVP-YNEAFGQPSTV--G 188

  Fly   191 RIPHYISQVPKTMGFWNRLHNHIMYYAEPL------------IHLVITRPVLSELMKTENAFPKL 243
            .||...||:....||.:||::....|...|            |...|.|||    ...::...:.
Worm   189 YIPQQGSQLAPEAGFLDRLNDVYRNYFYTLTMKRASQLQNTFIEKAIGRPV----PNWKDLVTRS 249

  Fly   244 QLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFF---DGIVYINMPYI--E 303
            .:.:.|::|.||:.......::.|||:.|..:.......:.|..|..|   :..|.|:...:  .
Worm   250 PIYITNSNPYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENIFAERESTVLISFGSVIRS 314

  Fly   304 YMNDQGLKA-MYTMIHGNPNVAFIW-----NVEQLEQLPAKKPNLLTLHV-NQSLQQDILAMQYV 361
            |......|| :..|....|.|.|||     :||..::||.      .:|: |...|..:||.:.:
Worm   315 YEMPDNFKAGIINMFKSLPEVTFIWKYEKDDVEFQKRLPK------NVHLKNWVPQPSLLADKRL 373

  Fly   362 KGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDA--LTR 424
            |.|:.||...|..|..:.|.|.:::|:..::..||. ::.|:.|.:    .:::..|:|.  |.:
Worm   374 KLFVTHGGLGSTMEVAYTGKPALMIPIFGDQPQNAD-MLSRHGGAV----AYDKFELADGDKLIK 433

  Fly   425 ILDE 428
            |:.:
Worm   434 IVKD 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	48/201 (24%)
H23N18.4	NP_504314.2	GT1_Gtf-like	21..466	CDD:340817	106/459 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100