Protein Alignment Ugt305A1 and ugt-8

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_504315.1
• Gene: ugt-8 / 186768
• WormBaseID: WBGene00019234
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 121/583 - (20%)
• Similarity: 223/583 - (38%)
• Gaps: 145/583 - (24%)

  Fly     6 LLPVFVLLGRFCSLEAANILCLVSTAKHNNP--GWSKPLFDALLAN-----GHSLLVISTAPNPE 63
            ||.:.::||   |:...|||..       ||  |.|...|.:.:||     ||::.:..  |...
 Worm     6 LLSILLVLG---SVSCKNILIF-------NPIFGLSHVKFISKMANIIADHGHNVTLFQ--PFHI 58

  Fly    64 PKKQVDGLV---------YYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALL 119
            ..|..:||:         ||  |:.||.:.:......|..:.|.:..|.:|          .|.:
 Worm    59 ALKNTEGLIKNKYIEIINYY--PDHYDELLKTETATFPAFWDSHLMNNPVL----------SAFM 111

  Fly   120 NSDTMSSKRPELTAQL-----------SMEYDLIITDVTQ----------GIECLMDSVSGWRSK 163
            ....::.:......||           |..:|:||::..:          .:.|:
 Worm   112 IPKAIAGEFERTATQLLKDKVALDDLKSRNFDVIISETFELTGMYIAHMLNVPCI---------- 166

  Fly   164 PVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMY------------- 215
            ||  .||.:.| ...::....:::..::.|  .|::....||.:||::  :|
 Worm   167 PV--WSAVRFT-IFNNIFGQPSSLGYSQQP--FSKLAPEAGFIDRLND--VYRNFFFTITMDGMG 224

  Fly   216 -YAEPLIHLVITRPV--LSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGG----LHIK 273
             |....|...:.||:  ..:|:|      :..:...|::..||:.......::.:||    |...
 Worm   225 QYQNDFIEKAVGRPLPYWKDLIK------EAPVYFTNSNEYLDFAVPTTATIVHIGGFTMDLEKM 283

  Fly   274 NQTSPLP-TYIQEFTEKFFDGIVYINMPYIEYMNDQGLKA-MYTMIHGNPNVAFIWNVEQLE-QL 335
            ....||| .|.:...|:....::........|......|| :..|....|:|.|||..|:.: :.
 Worm   284 KHVDPLPDKYAKILEERESTVLISFGSVIRSYQMPDNFKAGIIKMFESLPDVTFIWKYERDDVEF 348

  Fly   336 PAKKPNLLTLHVNQSL-QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRV 399
            ..|.|.  .:|:.:.: |..:||...||.|:.||...|..|..:.|.|.:::|:..::..|| .:
 Worm   349 QKKLPK--NVHLKKWVPQHSLLADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENA-NM 410

  Fly   400 MERNLGVMLQVKEFNQSSLSD----ALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQL 460
            :.|:.|.:    .:::..|:|    |:| |.|..|        ..|:....|..|::.   :.|.
 Worm   411 LARHGGAI----SYDKFELADGEKLAIT-IRDMVR--------NPKYNKNAQELLKVL---SHQP 459

  Fly   461 IAEPR--LFKHF----------AQTETLAQNFFVAN-SLDVLTVPLIVLLAAVVSLANLVYVL 510
            | :|:  |.||.          :|...:.|...:|: .|||:....::.:..|.....::.:|
 Worm   460 I-DPKLNLMKHLEFAMEFPNLRSQVPAINQMGLIAHYYLDVIFFLSLIFILTVYLTFKIISLL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	102/502 (20%)
ugt-8	NP_504315.1	GT1_Gtf-like	20..457	CDD:340817	102/499 (20%)