DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt305A1 and ugt-37

DIOPT Version :9

Sequence 1:	NP_001261394.1	Gene:	Ugt305A1 / 59217	FlyBaseID:	FBgn0042179	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_504811.2	Gene:	ugt-37 / 184293	WormBaseID:	WBGene00017332	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	542	Identity:	106/542 - (19%)
Similarity:	214/542 - (39%)	Gaps:	92/542 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ANILCLVSTAKHNNPGWSKPL---FDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVM 83
            |.|...:|.|.||...::..:   |..:....|:..||...|:.:.::      |.:...:.|:.
Worm    35 AKIADTLSEAGHNVTFFTPTIIRKFSKINYVKHTKHVIHLEPSEKLER------YGNQMEDVDIS 93

  Fly    84 KRHFLLEEP--REYISMVTL-NQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITD 145
            :  |..::.  .|...|:.| |::......:||.     |.|.:...:       .|::|::|.:
Worm    94 R--FWTDDSSMAEMFPMIKLFNEMFAEQAFVLGQ-----NLDVLDELK-------EMKFDVMIFE 144

  Fly   146 VTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYI----SQVPKTMGFW 206
              :..||....:.....:..:..|:....|:|:.      :|...|||..:    |:....|...
Worm   145 --RFAECAYPLLEYLEIETFIPSSSLLFDPNLLI------SIGEPRIPSTVPLPMSKFTDKMTMT 201

  Fly   207 NRLHNHIMYYAEPLIHLVIT-------RPVLS--ELMKTENAFPKLQLVLLNTHPTLDYVQNLPP 262
            .||.|.|   |.|:.|.::.       ||...  ::.|.|:.   ...:|.|::|.:||.:....
Worm   202 ERLLNAI---AVPIFHSLLPTHEFKSFRPPYQAIDIQKMEHL---SSFILSNSNPYIDYPRPTLE 260

  Fly   263 GVIEVGGLHIKNQTSPLPTYIQEFTEKFFD----------GIVYI--NMPYIEYMNDQGLKAMYT 315
            ..:::||:.:..:...:....:|: ::..|          |.|.:  :||.      :..|.:..
Worm   261 KNVQIGGISVDVENLKIHKVNEEW-DRILDMRQKTILVSFGSVMLSKDMPV------ENKKILAK 318

  Fly   316 MIHGNPNVAFIWNVE--QLEQLPAKKPNLLTLHVNQSLQQD-ILAMQYVKGFLNHGDSFSLQEAI 377
            .:...|.|.|||..|  ..:...::..|   :|.:..:.|. :||.:.:..|..|....|:.|..
Worm   319 TMKQFPEVTFIWKYEFNDTDLFASETEN---IHFSSWVPQTALLADRRLTAFFTHAGLGSVNEVS 380

  Fly   378 HYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEF-NQSSLSDALTRILDEERFISALHQAQLK 441
            :.|.|.::.|:..::..||:.:...|..:.:...:. |...:...|..||.::.:..:..:...:
Worm   381 YLGKPSIMCPIFADQMRNAKMLARHNGSIEISKYDLGNGEKIEKTLRTILFDDSYRLSAEKLAHQ 445

  Fly   442 FRTRPQSALELAVWHAE---QLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSL 503
            ...:|....||.:.|||   |....|.|..:..|...:  .:|:   :||..:.:...|..||.|
Worm   446 LANQPVKPKELLLRHAEFAAQFGRLPSLDPYSRQLSFV--EYFL---IDVAAILIFSSLLIVVVL 505

  Fly   504 ANLV-----YVLYTGGSKRQQT 520
            ..::     ::..|..|::.:|
Worm   506 FQIIKRLINFLPVTVDSRKVKT 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	46/237 (19%)
ugt-37	NP_504811.2	Glycosyltransferase_GTB_type	1..504	CDD:299143	101/517 (20%)
ugt-37	NP_504811.2	UDPGT	37..510	CDD:278624	102/521 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100