Protein Alignment Ugt305A1 and ugt-12

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_504309.1
• Gene: ugt-12 / 178880
• WormBaseID: WBGene00020592
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 136/603 - (22%)
• Similarity: 234/603 - (38%)
• Gaps: 152/603 - (25%)

  Fly     7 LPVFVLLGRFCSLEAANILCLVSTAKHNNP--GWSKPLF-----DALLANGHSLLVISTAPNPEP 64
            |..|:.|..|...|     |..|.....||  |:|...|     |.:..:||.:.:..  |....
 Worm     3 LGTFIFLLTFLFFE-----CYSSKILIFNPIFGFSHVKFISKMADIIADHGHHVTLFQ--PYHIA 60

  Fly    65 KKQVDGLV--------YYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGS------- 114
            .|.:||||        .|| |..|:    ..|..||:.:        ...|...|:|:
 Worm    61 LKNLDGLVKNKNIEILNYH-PTHYE----ELLKAEPQTF--------SFFWDSYLVGNPVIGAFL 112

  Fly   115 CRALLNSDTMSSKRPELTAQ------LSMEYDLIITDVTQ----------GIEC--LMDSVSGWR 161
            ...||..:...:....|:.|      ...::||:|.:..:          .:.|  :|.:|
 Worm   113 MPKLLGGEFKKTAMEVLSDQKLINELKDRKFDLVIAETFELTGFYLAHLLDVPCIPMMSAV---- 173

  Fly   162 SKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMY----------- 215
            ..|:.....|:  |.|:           ..:|...|.|....||::||::...:
 Worm   174 RYPIFNDQFGQ--PSLL-----------GHVPQIGSAVAGEAGFYDRLNDMFRFFFMGISQEQLN 225

  Fly   216 -YAEPLIHLVITRPV--LSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIK---- 273
             |....|...|.|||  ..:|:|      :..:.:.|::|.|||.......:::|||:.:.
 Worm   226 KYQNYFIEEAIGRPVPFWKDLVK------QSPIYITNSNPYLDYAVPSTAAIVQVGGITMDLKKL 284

  Fly   274 NQTSPLPTYIQEFTE--KFFDGIVYINMPYI--EYMNDQGLKA-MYTMIHGNPNVAFIWNVEQLE 333
            .|...||   :|:..  |..:..|.|:...:  .|...:..|| :..:....|:|.|||..|: :
 Worm   285 KQVGELP---EEYENILKERESTVLISFGSVIRSYEMPESFKAGLIKVFESLPDVTFIWKYEK-D 345

  Fly   334 QLPAKKPNLLTLHVNQSL-QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQ 397
            .|..:|.....:|:.:.: |..:||.:.||.|:.||...|..|..:.|.|.:|:|:..::.:||
 Worm   346 DLEFQKRLPKNVHLKKWIPQPSLLADKRVKLFITHGGLGSTMEVAYTGKPAIVVPIFGDQHHNA- 409

  Fly   398 RVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQ--AQLKFRTRPQSALELAVW----- 455
             ||....|..:...:|:          :.:.|:..:.:|:  :..|::...: ||:..::
 Worm   410 -VMLARHGGAVAYDKFD----------LKNGEKLTAVVHEMISSTKYQENAE-ALQHVLFNQPID 462

  Fly   456 -------HAEQLIAEPRLFKHFAQTETLAQNFFVAN-SLDVLTVPLIVLLAAVVSLANLVYVLYT 512
                   |.:..|..|   .|.||...:.|..|||: .||||   |.:|::::|       :.|.
 Worm   463 PKMNFLNHLDFAIKFP---NHRAQVPAINQLGFVAHYYLDVL---LFLLVSSIV-------ITYL 514

  Fly   513 GGSKRQQTLEKAVLKKRK 530
            ..|..::.|.|.:.||.|
 Worm   515 AISLLKKVLGKCLTKKTK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	108/515 (21%)
ugt-12	NP_504309.1	GT1_Gtf-like	21..456	CDD:340817	105/489 (21%)