Protein Alignment Ugt305A1 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 130/553 - (23%)
• Similarity: 213/553 - (38%)
• Gaps: 144/553 - (26%)

  Fly     6 LLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVIS---------TAPN 61
            ||..|:|.|...| |||.|| .:||...::......:...|..:||::.:::         .:.:
Human     8 LLVGFLLPGVLLS-EAAKIL-TISTVGGSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPGLSDS 70

  Fly    62 PEPKKQVDGLVYYHL------------PNEYDVM-----KRH---------FLLEEPREYISMVT 100
            |....:...::|...            ...|.|:     :.|         |.|||        |
Human    71 PASASRYPRILYLQKYCQFGLKDFKKEEKSYQVISWLAPEDHQREFKKSFDFFLEE--------T 127

  Fly   101 L------NQLLVWYEVLLGSCRALLN-SDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVS 158
            |      ..||...|.|...|...|| .|.|.|.:.|       .:|::|.:.......|:....
Human   128 LGGRGKFENLLNVLEYLALQCSHFLNRKDIMDSLKNE-------NFDMVIVETFDYCPFLIAEKL 185

  Fly   159 GWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYA--EPLI 221
            |.....:|..|.|.|...|        .|..:.:|.:.|.:...|.||.|:.|.:|:::  ....
Human   186 GKPFVAILSTSFGSLEFGL--------PIPLSYVPVFRSLLTDHMDFWGRVKNFLMFFSFCRRQQ 242

  Fly   222 HLVIT-------------RPVLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIK 273
            |:..|             |||||.|:.      |.:|..:|:....|:.:.|.|..:.|||| ::
Human   243 HMQSTFDNTIKEHFTEGSRPVLSHLLL------KAELWFINSDFAFDFARPLLPNTVYVGGL-ME 300

  Fly   274 NQTSPLPTYIQEFTEKFFD-GIVYI----------NMPYIEYMND------QGLKAMYTMIHGNP 321
            ....|:|..::.|..||.| |.|.:          |....:.||:      ||:.......|...
Human   301 KPIKPVPQDLENFIAKFGDSGFVLVTLGSMVNTCQNPEIFKEMNNAFAHLPQGVIWKCQCSHWPK 365

  Fly   322 NVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVL 386
            :|....||:.::.||               |.|:||...::.|:.||...|:.|||.:|||:|.:
Human   366 DVHLAANVKIVDWLP---------------QSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGI 415

  Fly   387 PLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALE 451
            ||..::..|..||..:..||.:|:|:....:|:..:.:|::::|:.||...|.:..|:.|.|..:
Human   416 PLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQ 480

  Fly   452 LAV-----------------------WHAEQLI 461
            ..|                       ||.:.|:
Human   481 RLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	65/258 (25%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	122/537 (23%)
		egt	<162..517	CDD:223071	93/389 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.030