Protein Alignment Ugt305A1 and ugt1a4

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001170815.3
• Gene: ugt1a4 / 100384901
• ZFINID: ZDB-GENE-080227-3
• Length: 520
• Species: Danio rerio
• Alignment Length: 596
• Identity: 133/596 - (22%)
• Similarity: 238/596 - (39%)
• Gaps: 143/596 - (23%)

  Fly     5 CLLPVFVLLGRFC--SLEAANILCLVSTAKHNNPGW--SKPLFDALLANGHSLLVISTAPNPE-- 63
            ||   ::|:|.|.  |.||..:|.:.|...|    |  .||:.:.|...|:.::|:.    ||
Zfish     3 CL---WLLVGLFLFGSAEAGKLLVIPSDGSH----WLGMKPVVEELGRRGNQVVVVI----PEAS 56

  Fly    64 ----PKKQVDGLVYYHLPNEYDVMKRHFLLE-EPREYIS----------MVTLNQLLVWYEVLLG 113
                |.::...|.|   |..|...:.|.:|| ...|.:|          .|...||.|....::.
Zfish    57 LSMGPSEKTTTLTY---PVNYTKAELHMVLEGNLTEILSTDFSTELSKFFVFFLQLKVLQNFIVR 118

  Fly   114 SCRALL-NSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGL--------- 168
            :...|| |.|.|...:       ..::|.|:||..:.:..:   .|.:.|.|.:.:
Zfish   119 NAEGLLFNEDLMKKLQ-------DCKFDAILTDPFEPVGVI---ASEYLSIPAIYMQVNLPCGVD 173

  Fly   169 SAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSEL 233
            |.....|...|.:...||       |:..|    |..|.|..|.:    ..|:..:..|.:.:|.
Zfish   174 SLASQCPSPPSYVPQRNT-------HFTDQ----MNIWQRCINLV----RTLLQHMACRYMYAEA 223

  Fly   234 MKTENAF--PKLQLVLLNTHPTL---------DYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFT 287
            .:..:.|  .:..:|.:....||         ::.:.|.|.::.:||:..| :..||...::||.
Zfish   224 DEIASRFLQRRASIVEIMNRATLWLMRFDFAFEFPRPLMPNMVMIGGMATK-KPKPLSKELEEFV 287

  Fly   288 ----EKFFDGIVYINMPYIEYMNDQGLKAMYTMIHGNPNVAFIW------------NVEQLEQLP 336
                |..|  :|:.....:..:.:...:..:......|. ..:|            ||:.::.||
Zfish   288 NGSGEHGF--VVFTLGSMVSQLPEAKAREFFEAFRQIPQ-RVLWRYTGPVPENAPKNVKLMKWLP 349

  Fly   337 AKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVME 401
                           |.|:|....|:.|:.||.|..:.|.|..|||:|:|||..::.:||||::.
Zfish   350 ---------------QNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVS 399

  Fly   402 RNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALELAVWHAEQL 460
            |.:...|.:.:.....|..||.::::::.:      :||:|      |.||...|:|||:..| .
Zfish   400 RGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIH------RDRPIEPLDLAVFWTE-F 457

  Fly   461 IAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAV-VSLANLVYVLYTGGSKRQQTLEKA 524
            :...:..:|. :......|:...:||||:...|::||..: |::.:.::..            :.
Zfish   458 VMRHKGAEHL-RPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCF------------RK 509

  Fly   525 VLKKRKKSKKS 535
            ..||.:|.||:
Zfish   510 CFKKSQKKKKA 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	110/499 (22%)
ugt1a4	NP_001170815.3	None