Protein Alignment Ugt305A1 and ugt1a4

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001170815.2
• Gene: ugt1a4 / 100384901
• ZFINID: ZDB-GENE-080227-3
• Length: 520
• Species: Danio rerio
• Alignment Length: 598
• Identity: 135/598 - (22%)
• Similarity: 236/598 - (39%)
• Gaps: 141/598 - (23%)

  Fly     1 MRALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGW--SKPLFDALLANGHSLLVISTAPNPE 63
            |..|.||....|||   |.||..:|.:.|...|    |  .||:.:.|...|:.::|:.    ||
Zfish     1 MACLWLLVGLFLLG---SAEAGKLLVIPSDGSH----WLGMKPVVEELGRRGNQVVVVI----PE 54

  Fly    64 ------PKKQVDGLVYYHLPNEYDVMKRHFLLE-EPREYIS----------MVTLNQLLVWYEVL 111
                  |.::...|.|   |..|...:.|.:|| ...|.:|          .|...||.|....:
Zfish    55 ASLSMGPSEKTTTLTY---PVNYTKAELHMVLEGNLTEILSTDFSTEVSKFFVFFLQLKVLQNFI 116

  Fly   112 LGSCRALL-NSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGL------- 168
            :.:...|| |.|.|...:       ...:|.|:||..:.:..:   .|.:.|.|.:.:
Zfish   117 VRNAEGLLFNEDLMKKLQ-------DCRFDAILTDPFEPVGVI---ASEYLSIPAIYMQVNLPCG 171

  Fly   169 --SAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLS 231
              |.....|...|.:...||       |:..|    |..|.|..|.:    ..|:..:..|.:.:
Zfish   172 VDSLASQCPSPPSYVPQRNT-------HFTDQ----MNIWQRCINLV----RTLLQHMACRYMYA 221

  Fly   232 ELMKTENAF--PKLQLVLLNTHPTL---------DYVQNLPPGVIEVGGLHIKNQTSPLPTYIQE 285
            |..:..:.|  .:..:|.:....||         ::.:.|.|.::.:||:..| :..||...::|
Zfish   222 EADEIASRFLQRRASIVEIMNRATLWLMRFDFAFEFPRPLMPNMVMIGGMATK-KPKPLSKELEE 285

  Fly   286 FT----EKFFDGIVYINMPYIEYMNDQGLKAMYTMIHGNPNVAFIW------------NVEQLEQ 334
            |.    |..|  :|:.....:..:.:...:..:......|. ..:|            ||:.::.
Zfish   286 FVNGSGEHGF--VVFTLGSMVSQLPEAKAREFFEAFRQIPQ-RVLWRYTGPVPENAPKNVKLMKW 347

  Fly   335 LPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRV 399
            ||               |.|:|....|:.|:.||.|..:.|.|..|||:|:|||..::.:||||:
Zfish   348 LP---------------QNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRL 397

  Fly   400 MERNLGVMLQVKEFNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALELAVWHAE 458
            :.|.:...|.:.:.....|..||.::::::.:      :||:|      |.||...|:|||:..|
Zfish   398 VSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIH------RDRPIEPLDLAVFWTE 456

  Fly   459 QLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAV-VSLANLVYVLYTGGSKRQQTLE 522
             .:...:..:|. :......|:...:||||:...|::||..: |::.:.::..
Zfish   457 -FVMRHKGAEHL-RPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCF------------ 507

  Fly   523 KAVLKKRKKSKKS 535
            :...||.:|.||:
Zfish   508 RKCFKKSQKKKKA 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	58/249 (23%)
ugt1a4	NP_001170815.2	UDPGT	19..508	CDD:278624	120/563 (21%)
		egt	<229..497	CDD:223071	68/294 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930