Protein Alignment Ugt305A1 and ugt2a3

DIOPT Version :9

• Sequence 1: NP_001261394.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001170814.2
• Gene: ugt2a3 / 100384900
• ZFINID: ZDB-GENE-080721-22
• Length: 532
• Species: Danio rerio
• Alignment Length: 585
• Identity: 127/585 - (21%)
• Similarity: 226/585 - (38%)
• Gaps: 142/585 - (24%)

  Fly    24 ILCLVSTAKHNNPGWS----------------KPLFDALLANGHSLLVI-----STAPNPEPKKQ 67
            :||.|..      |||                :.:.:||:...||:.|:     .|.|:.: |.:
Zfish    11 LLCGVDV------GWSGRVLVMPGEYSHWHNMRAIIEALVDRNHSVTVLVGSSSPTVPHTQ-KAR 68

  Fly    68 VDGLVYYHL------PNEYDVMKRHFLL----EEPREYISMVTLNQLLVWYEVLLGS-CRALLNS 121
            .|    ||:      ..|.|.:...|:.    |...:|.::..:.|::..:..|... |:.:...
Zfish    69 FD----YHVFKVNIEKEEADAVWSDFIYLWMNETATKYETVSNIFQVMSRFMTLTDEVCKGMFKE 129

  Fly   122 DTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENT 186
            |.:...|       ...||::.:|...               |...|.|..|...|:..|||...
Zfish   130 DLLQMLR-------ESHYDVLFSDPMM---------------PCSDLMAQTLNIPLVLSLRATFA 172

  Fly   187 INAARI-------PHYI------SQVPKTMGFWNRLHNHIMYYAEPL---IHLVIT--------- 226
            .:..|:       |.|:      ..:...|.|..|:.|.::|::..:   ::::.|
Zfish   173 YSFERMCGQMPAPPSYVPAASLRDHLTDRMSFMERVENMLLYFSHDVFFKLYMMFTFDRIYTEIR 237

  Fly   227 -RP-VLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEK 289
             :| .:.|.|      .|..:.|:.|:...:|.:..||....|||||.| ...||...::||.:.
Zfish   238 GKPTTMCETM------GKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCK-PAKPLSKEMEEFVQS 295

  Fly   290 FFD-GIVYINM-PYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSL- 351
            ..| |:|..:: ..|:.:..:....:...:...|. ..:|      :...|.|.  ||..|..:
Zfish   296 SGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQ-KVVW------RYSGKTPE--TLAPNTKIY 351

  Fly   352 ----QQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKE 412
                |.|:|.....|.|:.||.:..|.|||::|||:|.|||..::.:|...:..:...|:|.:..
Zfish   352 DWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINT 416

  Fly   413 FNQSSLSDALTRILDEERF------ISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHF- 470
            .....|.|||..:|:...:      :|.:|..|      |...|:.||:..| .:...:..||.
Zfish   417 LESKDLVDALKTVLNNPSYKESIMRLSRIHHDQ------PMKPLDQAVYWIE-FVMRNKGAKHLR 474

  Fly   471 AQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKS 535
            .|...|  :::..:.|||        .|.::|:|.|:..|:.   |....|.:..::|.:..:|:
Zfish   475 VQAHEL--SWYQYHCLDV--------AAFLLSIAALITFLWV---KACCFLFRRCVRKTRPERKT 526

  Fly   536  535
            Zfish   527  526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	61/231 (26%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	119/560 (21%)
		REC	<129..>178	CDD:302758	13/70 (19%)
		egt	<254..485	CDD:223071	64/249 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930