Protein Alignment Ugt305A1 and ugt1b5

DIOPT Version :10

• Sequence 1: NP_652703.1
• Gene: Ugt305A1 / 59217
• FlyBaseID: FBgn0042179
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001170813.1
• Gene: ugt1b5 / 100384899
• ZFINID: ZDB-GENE-080227-14
• Length: 528
• Species: Danio rerio
• Alignment Length: 540
• Identity: 124/540 - (22%)
• Similarity: 225/540 - (41%)
• Gaps: 144/540 - (26%)

  Fly    38 WS--KPLFDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVMKRHFLLEEPREYISMVT 100
            |:  |.:.:.:...||:::|:.    ||...::.       |.::.:.|:.     |.:|...|
Zfish    42 WTGVKAVAEEMGRRGHTVIVVI----PEISMRLG-------PGKHYITKKF-----PVKYKPDV- 89

  Fly   101 LNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLS---------MEYDLIITD----VTQGIEC 152
            |||::.          .|:|  |:|:....|..:::         ::|.:..|:    ..:.||.
Zfish    90 LNQMIA----------KLVN--TLSAPEQSLLKRVTSNIYNFGKVVDYFISTTESLFQEQELIEF 142

  Fly   153 L----MDSVSGWRSKPVLGLSAGKLTPDLMSLLR---AENTINA-----ARIPHYISQVPKTMGF 205
            |    .|:|....:.|...:.|..|:...:.:||   .|:...|     :.||...:|....|.|
Zfish   143 LRDQNFDAVLTDPAMPTGAILAYNLSVPAVYMLRGLMCESKATACPDPPSYIPRLFTQNSDHMNF 207

  Fly   206 WNRLHNHIMYYAEPL----------------IHLVITRPVLSELMKTENAFPKLQLVLLNTHPTL 254
            ..||.|.:....|||                :|..::   ::|::.|...:      |:....||
Zfish   208 GERLMNTLASLMEPLMCKLKFSAFEEVTSKFLHRDVS---MTEILSTGAVW------LMRYDFTL 263

  Fly   255 DYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTE--------KFFDGIVYINMPYIEYMNDQGLK 311
            ::.:.|.|.:..:||::.: ..:||...::||..        .|..|.:..:||  :...|...|
Zfish   264 EFPKPLMPNITNIGGINCE-VNNPLTKEVEEFVNGSGEHGIVVFSLGSLVSSMP--KEKADIFFK 325

  Fly   312 AMYTMIHGNPNVAFIW------------NVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGF 364
            | ::||   |. ..:|            ||:.::.||               |.|:|.....:.|
Zfish   326 A-FSMI---PQ-RVLWRYTGEIPNNVPENVKLMKWLP---------------QNDLLGHPKARAF 370

  Fly   365 LNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEE 429
            :.||.:..:.|.|.:|||:|:|||..::.:|..||..|.:||:|.:.:....:|.|||..:::..
Zfish   371 ITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDALNSVINNS 435

  Fly   430 RF------ISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHF--AQTETLAQNFFVANSL 486
            .:      :||:|      ..||...|:|||:..| .:...:...|.  |..|.   |:...:||
Zfish   436 SYKQKMQKLSAIH------NDRPIQPLDLAVFWTE-FVMRHKGADHLRPAAHEL---NWLQYHSL 490

  Fly   487 DVLTVPLIVLLAAVVSLANL 506
            ||:...|:::|  :|:||.|
Zfish   491 DVIGFMLLIVL--IVTLAML 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt305A1	NP_652703.1	GT1_Gtf-like	22..460	CDD:340817	110/490 (22%)
ugt1b5	NP_001170813.1	UDPGT	30..524	CDD:278624	124/540 (23%)