DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arts and AT4G27640

DIOPT Version :9

Sequence 1:	NP_001261957.1	Gene:	Arts / 59215	FlyBaseID:	FBgn0042177	Length:	1080	Species:	Drosophila melanogaster
Sequence 2:	NP_194494.2	Gene:	AT4G27640 / 828875	AraportID:	AT4G27640	Length:	1048	Species:	Arabidopsis thaliana

Alignment Length:	1128	Identity:	289/1128 - (25%)
Similarity:	523/1128 - (46%)	Gaps:	164/1128 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DTERIRESTAKMLKAYENPDSLLVLTQIVMSDRPVQERQVAAVLLKRRVKKLRHWQLVPAEHQAA 80
            |.:..|::..::.:..::|..:..|.|.:.:.:....||:|||||::|:  ..||..:..:.:..
plant    16 DNDARRQAEDQIKRLAKDPQVVPALVQHLRTAKTPNVRQLAAVLLRKRI--TGHWAKLSPQLKQH 78

  Fly    81 IKSNMLQVLIAVKEKTVKGTVAFIIGSLVRHEEDKQNSWREEILKFIYERCSSPDPIESERGSSI 145
            :|.::::.:.......|:...|.:: |:|.........| .::|.|:::...|......|....:
plant    79 VKQSLIESITVENSPPVRRASANVV-SVVAKYAVPAGEW-PDLLTFLFQCSQSAQEDHREVALIL 141

  Fly   146 FSSLMDAAPDQFSNHTDTIFPLLAGILVTAEANGNMATPTVHNMLA-GTCVLLPFISGHSDAEQI 209
            ||||.:...:.|..:    |..|..:|:....:.:.:...|..:.| |:     |:...:|.:::
plant   142 FSSLTETIGNTFRPY----FADLQALLLKCMQDESSSRVRVAALKAVGS-----FLEFTNDGDEV 197

  Fly   210 MVK---AVPLILKALAAFAEKGNSNEFMGAFDIIDSMAEYVPHLLTGNVKLLLEFCLMIARNKQF 271
             ||   .:|.||.........|..:..:.||:|.|.:.|....||..:||.:::|.|.::.|:..
plant   198 -VKFRDFIPSILDVSRKCIASGEEDVAILAFEIFDELIESPAPLLGDSVKAIVQFSLEVSCNQNL 261

  Fly   272 DASIRVQVLTFVGSLVRLKKKIIMKQKLLQPTLSVLFEVICQDDLKEGDDDYFSSESLNSPSNAA 336
            ::|.|.|.:..|..|.:.|...:.|.||:.|.|.|:..::.:...:|.|||.       :|..|:
plant   262 ESSTRHQAIQIVSWLAKYKYNSLKKHKLVIPILQVMCPLLAESSDQEDDDDL-------APDRAS 319

  Fly   337 AQTLDLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLNI 401
            |:.:|.:|:::....|: |:|:......||.....|.:|...:|||:|||.:.: |:.|:.:|||
plant   320 AEVIDTLAMNLPKHVFL-PVLEFASVHCQSTNLKFREASVTALGVISEGCFDLM-KEKLDTVLNI 382

  Fly   402 IKAGVLDSVMFVRTAAFFALGQFSEFLQPTICKFAPQILPVLFDYLNQLVLELKVGEPDSKHMDR 466
            :...:.|..:.||.||.||:|||:|.|||.|......:||.|...:.....|:|         ::
plant   383 VLGALRDPELVVRGAASFAIGQFAEHLQPEILSHYQSVLPCLLIAIEDTSEEVK---------EK 438

  Fly   467 MFYALETFCENLDEDIVPYLPTLMDRLFGVME--PQNSNQMREMALSAIAAVSAAAKENLMPYFP 529
            ..|||..||||:.|:|||.|..||.:|...:|  |:|   ::|..:|||.:|:|||::...||..
plant   439 SHYALAAFCENMGEEIVPLLDHLMGKLMAALENSPRN---LQETCMSAIGSVAAAAEQAFNPYAE 500

  Fly   530 RIMTVLQGCLV--KDCPKEMYSQRIQAIDTLAALCRELGKDNIIP------LADETMNFCLMMLE 586
            |::.:::..:|  ||......::..:.:..:|......|.:.|:|      ::...:.|
plant   501 RVLELMKFFMVLTKDEDLRARARSTELVGIVAMSVGRKGMEAILPPFIDAAISGFELEF------ 559

  Fly   587 DGPDDPEFRRSIYNLMSSLSSVVNESMASVFPKFIDRIMESVISSEDMVPNVSDNAEDDLALVDA 651
                 .|.|...:...|:::.:::::    |.:::.|:|..|.:        |.|.:|..|
plant   560 -----SELREYTHGFFSNVAEILDDT----FAQYLPRVMPLVFA--------SCNLDDGSA---- 603

  Fly   652 PDIEIDLEHTDDED---------DQDAYLGEND------------YIVEKEEAILSLKEFATHTG 695
                :|::.:|||:         |.||    :|            .:.||..|..:|..||.||.
plant   604 ----VDIDESDDENVNDFGGVSSDDDA----DDEPRVRNISVRTGVLDEKAAATQALGLFALHTK 660

  Fly   696 AAFAPYLQSAFENVYKMIDHPQGDVRMACIDSICSFITALHKL----DDAAGLKRACEI---AIP 753
            :||||||:.:.:.:.|...:...|||:..:..:...:.|.|.:    :|..|  :|.||   .:.
plant   661 SAFAPYLEESLKIMDKHSAYFHEDVRLQAVTGLKHILAAAHAIFQTHNDGTG--KANEILDTVMN 723

  Fly   754 KFAHIMRTDDQVAVV----LRMLDVLYDVFKYVPAINSQEHAELIFGCIRDIFTNKMACQFNEES 814
            .:...|..||...||    :.:.|::.| :.| |||  |::...:......:.|.|.|||..|:.
plant   724 NYIKTMTDDDDKEVVAQACISVADIMKD-YGY-PAI--QKYLSPLVDATLLLLTEKAACQQLEDE 784

  Fly   815 GGGDDECSEESENDEMLFENAANLFPMF----GLTLQPELFSLYFGRLYHFYIQRLAKVKERDLP 875
            ...||   :::.:||:|.:..::|.|.|    |...:| :|:.:|..|..|       .|....|
plant   785 SDIDD---DDTGHDEVLMDAVSDLLPAFAKCMGSQFEP-VFAQFFEPLMKF-------AKASRPP 838

  Fly   876 EQRAYIYGALADCCKALKGCCATYFDALRPIFIAGSRDSDAKARQNSYFALGEIVFHSEEKSFES 940
            :.|..:..:||:..:.:....::|.|.|.|:.:......:|..|:|:.|.:||:..:..|.:.:.
plant   839 QDRTMVVASLAEVAQDMGLPISSYVDRLMPLVLKELGSPEATNRRNAAFCVGELCKNGGETALKY 903

  Fly   941 YPTILQALSEAIVRESVP--AAMDNICGAVARLIVTNPDSVPLGQVLPVWLNHLPLKDDTVENDV 1003
            :..:|:.:| .:..:|.|  |..||..||.||:||.:|..|||.|||||:|..||||:|..|:..
plant   904 FGDVLRGIS-PLFGDSEPDLAVRDNAAGATARMIVVHPQLVPLNQVLPVFLRGLPLKEDQEESMA 967

  Fly  1004 IQKAFRVLYLKARPSIEAHLEQILAITIEASYKKQMPDVETTESAVALIKEIRANYPELFSK--- 1065
            :......|...:.|.|.:|:.:::.|.           .:..||.|..: |::|.....||.
plant   968 VYTCIYSLVSSSNPQIFSHVPELVKIF-----------GQVLESPVEKV-EVKAIVGRTFSHLIS 1020

  Fly  1066 ---------VSNMNPEVFNYVQA 1079
                     :|::.|...|.:.|
plant  1021 VYGNQLQPIISSLPPSQANVLAA 1043

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arts	NP_001261957.1	IBN_N	29..90	CDD:197981	14/60 (23%)
		HEAT repeat	356..384	CDD:293787	8/27 (30%)
		HEAT repeat	397..427	CDD:293787	13/29 (45%)
		HEAT repeat	438..473	CDD:293787	8/34 (24%)
AT4G27640	NP_194494.2	KAP95	13..668	CDD:227540	184/721 (26%)
		HEAT repeat	40..72	CDD:293787	12/33 (36%)
		HEAT repeat	82..109	CDD:293787	4/27 (15%)
		HEAT repeat	118..144	CDD:293787	5/25 (20%)
		HEAT repeat	157..187	CDD:293787	6/34 (18%)
		HEAT repeat	335..366	CDD:293787	10/31 (32%)
		HEAT repeat	378..408	CDD:293787	13/29 (45%)
		HEAT repeat	419..445	CDD:293787	8/34 (24%)
		HEAT repeat	458..487	CDD:293787	11/31 (35%)
		HEAT repeat	828..850	CDD:293787	6/28 (21%)
		Vac14_Fab1_bd	848..928	CDD:403838	19/80 (24%)
		HEAT repeat	866..894	CDD:293787	8/27 (30%)
		HEAT repeat	906..938	CDD:293787	12/32 (38%)
		HEAT repeat	947..977	CDD:293787	13/29 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	194	1.000	Domainoid score	I918
eggNOG	1	0.900	-	-		E1_KOG2171
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5835
Inparanoid	1	1.050	322	1.000	Inparanoid score	I699
OMA	1	1.010	-	-		QHG54177
OrthoDB	1	1.010	-	-		D331433at2759
OrthoFinder	1	1.000	-	-		FOG0005113
OrthoInspector	1	1.000	-	-		otm3515
orthoMCL	1	0.900	-	-		OOG6_102877
Panther	1	1.100	-	-	O	PTHR10527
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4732
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840