Protein Alignment Arts and imb-2

DIOPT Version :9

• Sequence 1: NP_001261957.1
• Gene: Arts / 59215
• FlyBaseID: FBgn0042177
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001309574.1
• Gene: imb-2 / 175094
• WormBaseID: WBGene00002076
• Length: 889
• Species: Caenorhabditis elegans
• Alignment Length: 878
• Identity: 175/878 - (19%)
• Similarity: 337/878 - (38%)
• Gaps: 200/878 - (22%)

  Fly     5 ILDIINGILAIDTERIRESTAKMLKAYENPDSLLVLTQIVMSDR----PVQERQVAAVLLKRRVK 65
            ::.::....:.|.:..|....::::..|:......|..| :||.    ....|.:|.:|||..::
 Worm    13 VIQLLQHAHSTDRDVQRNVQVQLVQLNEHQKFCCYLVYI-LSDMKEMIDATSRSLAGLLLKNNIR 76

  Fly    66 KLRHWQLVPAEHQAAIKSNMLQVLIAVKEKTVKGTVAFIIGSLVRHEEDKQNSWREEILKFIYER 130
              ..|...|.:.:..:::..|: .|..:|..::.||..|:.::|.  |:....| .::|..:...
 Worm    77 --AKWNKYPQDVKFFVRTTCLK-SIGDQEPLIRATVGIIVTTIVM--EENMCDW-PDLLDTLATV 135

  Fly   131 CSSPDPIESERGSSIFSSLMDAAPDQFSNHTDTIFPLLAGILVTAEANGNMATPTVHNMLAGTCV 195
            ...||.:..|........:.:.:.|::  .::.:.|::..:||..|.:.........|.:  .|:
 Worm   136 LMQPDELMQEGALGALQKVFEDSADRY--ESEFLRPIMPKLLVFYEHHAAKMRALAMNCV--NCI 196

  Fly   196 LL-----------PFISG----HSDAEQIMVKAVPLILKALAAFAEKGNSNEFMGAFDIIDSMAE 245
            |:           .|::.    |:|.::.:.|.   :.::|....:..           |:.|..
 Worm   197 LMVNNDPIDFAIDQFLTSLFARHNDNDEEVQKQ---LCRSLTLLLDTH-----------IEKMMP 247

  Fly   246 YVPHLL--------TGNVKLLLEFC---LMIARNKQFDASIRVQVLTFVGSLV------------ 287
            ::|:::        ..|..:.||.|   |.||.|...   .|..||..:..|:
 Worm   248 HLPNVIEYIIKKTQDHNESIALEACEFWLSIAENSDI---CRTMVLPHLDKLIPVLLGSMRYSET 309

  Fly   288 --RLK---------------KKIIMKQKLLQPTLSVLFEVICQDDLKEGDDDYFSSESLNSPSNA 335
              .||               |....|.|  |..|..|.|   .||.::.|||.......|. ...
 Worm   310 DPALKANDEDSSVPDREEDIKPRFHKSK--QHGLGGLVE---SDDEEDEDDDDDGGGDWNI-RRC 368

  Fly   336 AAQTLDLMALHMVPDKFIPPLLDLLEPALQSPEPVLRRSSFICMGVIAEGCSEAIGKKYLEVMLN 400
            :|.:||::|.....| .:..|..||:..|.:...:::.|..:.:|.|||||.:.: ..:|..::.
 Worm   369 SAASLDVLASIFGKD-LLDKLFPLLKDTLMNDNWLVKESGILALGAIAEGCMDGV-VPHLGELIP 431

  Fly   401 IIKAGVLDSVMFVRTAAFFALGQFSEFL-----------------------------QPTICK-F 435
            .:.|.:.|....||:...:.|.::|..:                             |...|. |
 Worm   432 FMLAMMFDKKPLVRSITCWTLSRYSSHIASDENFRQQFFKDVLANLLRCSLDGNKKVQEAACSAF 496

  Fly   436 A-------PQILPVLFDYLNQLVLELKVGEPDSKHMDRMFYALETFCENLDEDI--VPYLPTLMD 491
            |       .|::|.|.:.|:|||...:..:  :|::..::.|:.|...::.:.:  ..|:..||.
 Worm   497 ATLEEEAGEQLIPFLGEILDQLVKAFQCYQ--AKNLLILYDAIGTLANSVGDALSHPVYVQMLMP 559

  Fly   492 RLFGVMEPQNSNQMREM--ALSAIAAVSAAAKENLMPY----FPRIMTVLQGCLVKDCPKEMYSQ 550
            .|....| :.|::.:|:  .|..|:|:.:|..::.:||    |.|..::::.|:.::....|...
 Worm   560 PLMEKWE-RLSDEDKELFPLLECISAIVSAMGQSFLPYIQPVFTRCCSLIEKCVQQNQQHIMAPD 623

  Fly   551 RIQ---------AIDTLAALCRELGKDNIIPLAD-----ETMNFCLMMLEDGPDDPEFRRSIYNL 601
            :::         |:|.|:.|...| .:::.||..     |.|.||.:.:     .|:.|:|.:.|
 Worm   624 QVEAPETDFIIVALDLLSGLAESL-PEHMDPLVANSKLVELMLFCSLDV-----TPDVRQSCFAL 682

  Fly   602 MSSLSSVVNESMASVFPK---------FIDRIMESVISSEDMVPNVSDNAEDDLAL--------V 649
            :..|:....|   .|.|:         ||..:.:::..|:..|.|.:..|..:|||        .
 Worm   683 LGDLTKACPE---RVLPQSKILQFAGNFIFFLAQNLDPSKISVCNNAIWALGELALKMGPAMKQF 744

  Fly   650 DAPDIEIDLEHTDDEDDQDAYLGENDYIVEKEEAILSLKEFATHTGAAFAPYL------------ 702
            ..|.||..:...:.:.:....|.||..|..........:|.|.|......|..
 Worm   745 IGPIIEPLIVVINSQQNMQRTLLENTAITIGRLGQCCGEELAPHISRFVRPCCYSLRNIKDNAEK 809

  Fly   703 QSAFENVYKMID-HPQG---DVRMACIDSICSF 731
            :|||..:..||: :|.|   |....| |:|.|:
 Worm   810 ESAFIGLCNMINMNPVGVLNDFIFWC-DAIASW 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arts	NP_001261957.1	IBN_N	29..90	CDD:197981	13/64 (20%)
		HEAT repeat	356..384	CDD:293787	7/27 (26%)
		HEAT repeat	397..427	CDD:293787	6/29 (21%)
		HEAT repeat	438..473	CDD:293787	9/34 (26%)
imb-2	NP_001309574.1	KAP95	15..764	CDD:227540	155/796 (19%)
		HEAT repeat	128..156	CDD:293787	4/27 (15%)
		HEAT repeat	169..201	CDD:293787	7/33 (21%)
		HEAT repeat	210..236	CDD:293787	5/28 (18%)
		HEAT repeat	249..278	CDD:293787	6/28 (21%)
		HEAT repeat	388..416	CDD:293787	7/27 (26%)
		HEAT repeat	428..458	CDD:293787	6/29 (21%)
		HEAT repeat	467..498	CDD:293787	3/30 (10%)
		HEAT repeat	512..539	CDD:293787	6/28 (21%)
		HEAT repeat	554..585	CDD:293787	8/31 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910