DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ea and CD81

DIOPT Version :9

Sequence 1:NP_525012.2 Gene:Tsp42Ea / 59178 FlyBaseID:FBgn0029508 Length:226 Species:Drosophila melanogaster
Sequence 2:NP_004347.1 Gene:CD81 / 975 HGNCID:1701 Length:236 Species:Homo sapiens


Alignment Length:228 Identity:50/228 - (21%)
Similarity:98/228 - (42%) Gaps:21/228 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVT-------MIILGTIILL 65
            :||:||:||.:..:.|.:::.....|....:..:.....|..:..|.|       :|.:|.:::.
Human    10 IKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMF 74

  Fly    66 ISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSD 130
            :.:.||.|||:||.|:..|:...|.:|...::|..|:.:|.||:..:.:....::|........|
Human    75 VGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDD 139

  Fly   131 YMDAIQI------SMKCCGRS---GYTDYAYQGKFPPSCCSDTNNCRWETVYRRGCKVTFVEFWD 186
            ..:|..:      ::.|||.|   ..|....:....||..:..:|     :::..|.....:.:.
Human   140 ANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISN-----LFKEDCHQKIDDLFS 199

  Fly   187 RNSDIIKYAGLVIAAIEFVGFVFACCLANSIRN 219
            ....:|..|.:|:|.|.....:.:..|...|||
Human   200 GKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRN 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EaNP_525012.2 Tetraspannin 8..217 CDD:278750 47/224 (21%)
tetraspanin_LEL 104..188 CDD:239401 15/92 (16%)
CD81NP_004347.1 Tetraspannin 10..226 CDD:395265 46/220 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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