Protein Alignment Tsp42Ea and CD53

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 61/216 - (28%)
• Similarity: 114/216 - (52%)
• Gaps: 22/216 - (10%)

  Fly     5 ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLISWF 69
            :.::||:||.||||..|||..::.||..|... .|.......|.:..:....:|:|:||:::::.
Human     6 LKLLKYVLFFFNLLFWICGCCILGFGIYLLIH-NNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFL 69

  Fly    70 GCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMG----DVVEKAWNHRTSRSD 130
            ||.|:|:|:.|:.|::.|||.::::.::.|.|.::|.:.|..|.:.    |.:.:..:..::::.
Human    70 GCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAA 134

  Fly   131 YMDAIQISMKCCGRSGYTDYAYQGKFPPSCCSDTNNCRWETVYRRGCKVTFVEFWDRNSDIIKYA 195
            : |:||..::|||.:|.:|:. .|. |.||.||..        ..||... ...|..::.:  |.
Human   135 W-DSIQSFLQCCGINGTSDWT-SGP-PASCPSDRK--------VEGCYAK-ARLWFHSNFL--YI 185

  Fly   196 GLV---IAAIEFVGFVFACCL 213
            |::   :..||.:|..||..|
Human   186 GIITICVCVIEVLGMSFALTL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/213 (29%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	61/213 (29%)
		CD53_like_LEL	104..186	CDD:239417	22/95 (23%)