Protein Alignment Tsp42Ea and CD37

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 69/282 - (24%)
• Similarity: 111/282 - (39%)
• Gaps: 69/282 - (24%)

  Fly     2 SCGISMVKYILFIFNLLCSICGILLIVFGA-LLFSKVRNMDDFAEALRTQQVPV-----TMIILG 60
            || :|::||.||:|||...:.|.|:..||. :|..|.    .|...:....||:     .:.|.|
Human     6 SC-LSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKT----SFVSFVGLAFVPLQIWSKVLAISG 65

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWN-- 123
            ...:.|:..||.||::|..|:...|..:|.:|...|:.|.|.:..|:.:....:.|||||...
Human    66 IFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKY 130

  Fly   124 ----HRTSRSDYMDAIQISMKCCGRSGYTDY----------AYQGKFPPSC--CSDTNN------ 166
                ..|:..:..|.:|..::|||.....|:          :...:.|.||  .|.||:
Human   131 GTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDK 195

  Fly   167 ---------------------CRWET---VYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGF 207
                                 |....   :||.|| ...::.|..| ::|...|:.:.    ||.
Human   196 VILPQLSRLGHLARSRHSADICAVPAESHIYREGC-AQGLQKWLHN-NLISIVGICLG----VGL 254

  Fly   208 VFACCLANSI----RNYRRRAE 225
            :....:..|:    |..||:.|
Human   255 LEMTVMVLSVQLQRRALRRKCE 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/260 (23%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	55/249 (22%)
		CD37_CD82_like_LEL	108..243	CDD:239413	26/136 (19%)