Protein Alignment Tsp42Ea and TSPAN10

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_114151.3
• Gene: TSPAN10 / 83882
• HGNCID: 29942
• Length: 355
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 68/267 - (25%)
• Similarity: 108/267 - (40%)
• Gaps: 49/267 - (18%)

  Fly     1 MSCGISMVKYILFIFNLLCSICGILLIVFGAL-LFSKVRNMDDFAEALRTQQVPVTMIILGTIIL 64
            :|.|.|.|||::|:.|...|:.|:|.:..|.. |..|.....|....|...  |:..:.||.:::
Human    69 LSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPAD--PMLGLALGGLVV 131

  Fly    65 -LISWFGCCGAIRESYCMSMTYS--ILLFVLMIGQL-ALVIYMWVQKDKYLEIMGDVVEKAWNHR 125
             .:|..|..||:.|:.|:...:|  ||.|:::.... |||:.:|......||   ..:..|..|.
Human   132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLE---HTLRVAIAHY 193

  Fly   126 TSRSD---YMDAIQISMKCCGRSGYTDYAYQGKF------------PPSCCSD--------TNNC 167
            ....|   .:|.:|:.::|||.:.|.|:.....|            |.|||.|        .:.|
Human   194 QDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQC 258

  Fly   168 RW-----------ETVYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVG--FVFACCLANSIRN 219
            .:           ..||..||... :..|.| :::....|..||.:...|  .:.|..|..::.
Human   259 GFGVLRLDADAAQRVVYLEGCGPP-LRRWLR-ANLAASGGYAIAVVLLQGAELLLAARLLGALA- 320

  Fly   220 YRRRAEY 226
            .||.|.|
Human   321 ARRGAAY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/247 (25%)
TSPAN10	NP_114151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Tetraspanin	76..226	CDD:459767	42/154 (27%)
		oculospanin_like_LEL	172..291	CDD:239420	26/123 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..355		1/1 (100%)