Protein Alignment Tsp42Ea and Cd82

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_113985.2
• Gene: Cd82 / 83628
• RGDID: 69070
• Length: 266
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 68/269 - (25%)
• Similarity: 116/269 - (43%)
• Gaps: 46/269 - (17%)

  Fly     1 MSCG-ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQ----QVPVTMII-L 59
            |..| :.:.||.||:||||..|.|.:::.||..:.:   :...|...|:|.    ||...:.| :
  Rat     1 MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILA---DKSSFISVLQTSSSSLQVGAYVFIGV 62

  Fly    60 GTIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMG----DVVEK 120
            |.|.:|:.:.||.||:.|..|:...|.:.|.:::|.|:.:.:..:...||..:.||    |:::.
  Rat    63 GAITMLMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKQEMGNTVMDIIQN 127

  Fly   121 -AWNHRTSRSDYMDAIQISMKCCG--------RSGYTDYAYQGKFPPSC---------------- 160
             :.|..:||.:..|.:|..:||||        |:.....:.:..:|.||
  Rat   128 YSVNASSSREEAWDYVQAQVKCCGWVSPSNWTRNPVLKNSTKTTYPCSCEKTKEEDNQLIVKKGF 192

  Fly   161 CSDTNNCRWET------VYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSI-- 217
            |...|:...|.      |:..||......:...|..|:......:|.||.:|...:.||...|
  Rat   193 CESDNSTASENSPEDWPVHPEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHS 257

  Fly   218 RNYRRRAEY 226
            .:|.:..:|
  Rat   258 EDYSKVPKY 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	63/246 (26%)
Cd82	NP_113985.2	Tetraspanin	24..253	CDD:459767	54/231 (23%)
		CD37_CD82_like_LEL	106..228	CDD:239413	25/121 (21%)