Protein Alignment Tsp42Ea and Tspan17

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_006517477.1
• Gene: Tspan17 / 74257
• MGIID: 1921507
• Length: 281
• Species: Mus musculus
• Alignment Length: 261
• Identity: 66/261 - (25%)
• Similarity: 110/261 - (42%)
• Gaps: 63/261 - (24%)

  Fly     3 CGISMVKYILFIFNLLCSICGILLIVFGAL------LFSKVRNMDDFAEALRTQQVPVTM-IILG 60
            ||    ||.||.||::..:.|.|.:..|..      :.|.:..:.|....     .||.: :::|
Mouse    16 CG----KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGL-----DPVWLFVVVG 71

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSI---LLFVLMI--GQLALVIYMWVQKDKYLEIMGDVVEK 120
            .::.::.:.||.||:||:..:...:|:   |:|.|.:  |.||.|...|::....|.|..:|  |
Mouse    72 GVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNV--K 134

  Fly   121 AWNHRTSRSDYMDAIQISMKCCGRSGYTDYAYQGKF--------------PPSCC-----SDTNN 166
            |:.......:.:|..|....|||..|..|:.....|              |.|||     .|..|
Mouse   135 AYRDDLDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLN 199

  Fly   167 --CRWE-----------TVYRRGCKVTFVEFWDRNSDIIKYAGLV--IAAIEFVGFVFACCLANS 216
              |.::           ::|.:||...| |.| ...::|..||::  ||.::    :|..|||.:
Mouse   200 TQCGYDIRLKLELEQQGSIYTKGCVGQF-EKW-LQDNLIVVAGVLVGIALLQ----IFGLCLAQN 258

  Fly   217 I 217
            :
Mouse   259 L 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	63/252 (25%)
Tspan17	XP_006517477.1	Tetraspanin	18..260	CDD:459767	64/255 (25%)
		TM4SF9_like_LEL	115..235	CDD:239412	28/123 (23%)