Protein Alignment Tsp42Ea and UPK1B

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 55/259 - (21%)
• Similarity: 96/259 - (37%)
• Gaps: 56/259 - (21%)

  Fly    12 LFIF-NLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTM---IILGTIILLISWFGCC 72
            |.|| |::...|||.|........|...::....||.....:....   |.:|..:..:|..|..
Human    14 LLIFGNVIIGCCGIALTAECIFFVSDQHSLYPLLEATDNDDIYGAAWIGIFVGICLFCLSVLGIV 78

  Fly    73 GAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLE--IMGDVVEKAWNHRTSRSD----- 130
            |.::.|..:.:.|.||:|::...::|..|....|:|.:..  .:..::|:..|:....:|
Human    79 GIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLERYQNNSPPNNDDQWKN 143

  Fly   131 -----YMDAIQISMKCCGRSGYTDY-AYQGKF-----------PPSCCSDTNNCRWETVYRRGCK 178
                 ..|.:.:...|||.:|.:|: .|...|           |..||. .||.: |.:....||
Human   144 NGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCV-MNNLK-EPLNLEACK 206

  Fly   179 VTFVEFW-------------DRNSDIIKYAGLVIAAIEF---VGFVFACCLANSIRNYRRRAEY 226
            :....|:             :|::..:.:.|..|....|   :|.:|          |..|.||
Human   207 LGVPGFYHNQGCYELISGPMNRHAWGVAWFGFAILCWTFWVLLGTMF----------YWSRIEY 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	51/246 (21%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	30/146 (21%)
		uroplakin_I_like_LEL	118..230	CDD:239409	21/113 (19%)