Protein Alignment Tsp42Ea and TSPAN4

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001426622.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 330
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 65/238 - (27%)
• Similarity: 111/238 - (46%)
• Gaps: 43/238 - (18%)

  Fly     3 CG-----ISMVKYILFIFNLLCSI--CGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILG 60
            ||     :..|||::|.||||..:  ||:|.:  |..|.:...:....:.:..:......:||.|
Human    91 CGMARACLQAVKYLMFAFNLLFWLGGCGVLGV--GIWLAATQGSFATLSSSFPSLSAANLLIITG 153

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFV--LMIGQLALVIYMWVQK-DKYLE---------- 112
            ..::.|.:.||.|||:|:.|:.:|:.:||.:  |:...:|::.:.:..| |:|.:
Human   154 AFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 218

  Fly   113 -IMGDV-VEKAWNHRTSRSDYMDAIQISMKCCGRSGYTDY--AYQG-KFPPSCCSD-TNNCRWE- 170
             ..|:| :..||:          .||...:|||.|.|||:  .|.. :.|.|||.: :.:|...
Human   219 GTQGNVGLTNAWS----------IIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHA 273

  Fly   171 --TVYRRGCKVTFVEFW-DRNSDIIKYAGLVIAAIEFVGFVFA 210
              |.::..|..| |:.| ..|...:...||..|.::.:|..||
Human   274 PGTWWKAPCYET-VKVWLQENLLAVGIFGLCTALVQILGLTFA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	63/228 (28%)
TSPAN4	NP_001426622.1	None