Protein Alignment Tsp42Ea and TSPAN6

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 61/230 - (26%)
• Similarity: 107/230 - (46%)
• Gaps: 19/230 - (8%)

  Fly     5 ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEAL--RTQQVPVTMIILGTIILLIS 67
            |:..|.:|.|:..:..|.|::|:..|  ::.|| :::::...|  :...||..:|..||:|:|:.
Human    14 ITCFKSVLLIYTFIFWITGVILLAVG--IWGKV-SLENYFSLLNEKATNVPFVLIATGTVIILLG 75

  Fly    68 WFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDY- 131
            .|||....|.|..|...|::.|.::.:.:|...|..:|.:.:......:..|||.....|..||
Human    76 TFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYR 140

  Fly   132 ---MDAIQISMKCCGRSGYTDYA----YQGK-FPPSCCSDTNNCR----WETVYRRGCKVTFVEF 184
               :|.||.::.|||.:.|.|:.    |..| ||.|||. ..:|.    .:.|...||.:..:..
Human   141 SHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCK-LEDCTPQRDADKVNNEGCFIKVMTI 204

  Fly   185 WDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIRN 219
            .:....::......:|..:.:|...|.||:.:|.|
Human   205 IESEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	58/221 (26%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	58/221 (26%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	26/97 (27%)