Protein Alignment Tsp42Ea and TSPAN8

DIOPT Version :9

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001356689.1
• Gene: TSPAN8 / 7103
• HGNCID: 11855
• Length: 237
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 70/241 - (29%)
• Similarity: 117/241 - (48%)
• Gaps: 32/241 - (13%)

  Fly     4 GIS-MVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVT-------MIILG 60
            |:| .:||.:|.||.|..:||||::.    |...||..:|......::.|..:       :|.:|
Human     3 GVSACIKYSMFTFNFLFWLCGILILA----LAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVG 63

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHR 125
            .||:::.:.||||||:||.||.:.:.|.|.::::.|:|..|...|.|.|...|:.:.:.:  |.:
Human    64 AIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYE--NTK 126

  Fly   126 ------TSRSDYMDAI---QISMKCCGR-SGYTDYAYQGKFPPSCCSDTNNCR------WETVYR 174
                  .|...:.:||   |...||||. :|..|:....:..|..|:..:..|      .:.||:
Human   127 LLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQSYNGKQVYK 191

  Fly   175 RGCKVTFV-EFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIRN 219
            ..| ::|: :|..:|..|:......:|.||.:|.||:..|...|.|
Human   192 ETC-ISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspannin	8..217	CDD:278750	66/232 (28%)
		tetraspanin_LEL	104..188	CDD:239401	23/100 (23%)
TSPAN8	NP_001356689.1	Tetraspannin	8..230	CDD:334016	65/228 (29%)
		TM4SF3_like_LEL	106..206	CDD:239407	23/102 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910